Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2179440..2179657 Replicon chromosome
Accession NZ_CP019592
Organism Staphylococcus aureus strain GD5

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag BZJ79_RS11150 Protein ID WP_001802298.1
Coordinates 2179553..2179657 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2179440..2179495 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BZJ79_RS11130 2175579..2176244 - 666 WP_001024099.1 SDR family oxidoreductase -
BZJ79_RS11135 2176396..2176716 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
BZJ79_RS11140 2176718..2177698 + 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
BZJ79_RS11145 2177964..2179055 + 1092 WP_000495673.1 hypothetical protein -
- 2179440..2179495 + 56 - - Antitoxin
BZJ79_RS11150 2179553..2179657 - 105 WP_001802298.1 hypothetical protein Toxin
BZJ79_RS11160 2180337..2180495 + 159 WP_001792784.1 hypothetical protein -
BZJ79_RS11165 2180931..2181023 + 93 WP_000220902.1 hypothetical protein -
BZJ79_RS11170 2181153..2182010 - 858 WP_000370942.1 Cof-type HAD-IIB family hydrolase -
BZJ79_RS11175 2182078..2182860 - 783 WP_084578720.1 ABC transporter ATP-binding protein -
BZJ79_RS11180 2183150..2183758 - 609 WP_000101714.1 TIR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T72759 WP_001802298.1 NZ_CP019592:c2179657-2179553 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T72759 NZ_CP019592:c2179657-2179553 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT72759 NZ_CP019592:2179440-2179495 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References