Detailed information of TA system TA072751

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1006893..1007142
• Replicon: chromosome
• Accession: NZ_CP019592
• Organism: Staphylococcus aureus strain GD5

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: BZJ79_RS05010
• Protein ID: WP_000623369.1
• Coordinates: 1006893..1007000 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	1006995..1007142 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BZJ79_RS04985	1003567..1004136	-	570	WP_000287265.1	competence protein ComK	-
BZJ79_RS04990	1004346..1004564	+	219	WP_000876826.1	IDEAL domain-containing protein	-
BZJ79_RS04995	1004645..1005631	-	987	WP_000668814.1	lipoate--protein ligase	-
BZJ79_RS05000	1005830..1006006	+	177	WP_000214898.1	YkvS family protein	-
BZJ79_RS05005	1006021..1006623	+	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
BZJ79_RS05010	1006893..1007000	+	108	WP_000623369.1	putative holin-like toxin	Toxin
-	1006995..1007142	-	148	-	-	Antitoxin
BZJ79_RS05015	1007635..1007919	+	285	WP_000790905.1	lactococcin 972 family bacteriocin	-
BZJ79_RS05020	1007963..1009927	+	1965	WP_000870811.1	bacteriocin-associated integral membrane family protein	-
BZJ79_RS05025	1009930..1010250	+	321	WP_000668623.1	YxeA family protein	-
BZJ79_RS05030	1010247..1010888	+	642	WP_000571192.1	ABC transporter ATP-binding protein	-
BZJ79_RS05035	1010976..1011266	-	291	WP_001796515.1	hypothetical protein	-
BZJ79_RS05040	1011356..1011544	+	189	WP_157958947.1	poly(glycerol-phosphate) alpha-glucosyltransferase	-
BZJ79_RS05045	1011633..1011989	-	357	WP_000766009.1	DoxX family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T72751 WP_000623369.1 NZ_CP019592:1006893-1007000 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T72751 NZ_CP019592:1006893-1007000 [Staphylococcus aureus]
GTGATATCTATTGCAAATGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTCACTTTCATTGGTGTAGTAGTCGC
AATAATTAATTTAAACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 148 bp

>AT72751 NZ_CP019592:c1007142-1006995 [Staphylococcus aureus]
CAATTAAATAAAAGATATGTTACTATAAAAATGTAAAAAGACGACATGCAGTAACATGTCGCCTAATGAGCCCGTTAAAA
AGACGGTGACTAAATGAGATTTGCTTTAACCATCATTCGTTGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Antitoxin