Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1935778..1935960 Replicon chromosome
Accession NZ_CP019590
Organism Staphylococcus aureus strain C2406

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag BJN19_RS15200 Protein ID WP_001801861.1
Coordinates 1935778..1935873 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1935901..1935960 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJN19_RS09830 1931438..1932064 + 627 Protein_1843 hypothetical protein -
BJN19_RS09835 1932105..1932449 + 345 WP_000627551.1 DUF3969 family protein -
BJN19_RS09840 1932547..1933098 + 552 WP_000414205.1 hypothetical protein -
BJN19_RS09845 1933316..1933957 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
BJN19_RS09850 1934071..1934256 - 186 WP_000809857.1 hypothetical protein -
BJN19_RS09855 1934258..1934434 - 177 WP_000375476.1 hypothetical protein -
BJN19_RS09860 1934445..1934828 - 384 WP_000070811.1 hypothetical protein -
BJN19_RS09870 1935432..1935575 - 144 WP_001549059.1 transposase -
BJN19_RS15200 1935778..1935873 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1935901..1935960 - 60 - - Antitoxin
BJN19_RS09875 1935996..1936097 + 102 WP_001791893.1 hypothetical protein -
BJN19_RS09880 1936075..1936251 - 177 Protein_1853 transposase -
BJN19_RS09885 1936445..1936822 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - lukD / hlgA 1905413..2010519 105106


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T72723 WP_001801861.1 NZ_CP019590:1935778-1935873 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T72723 NZ_CP019590:1935778-1935873 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT72723 NZ_CP019590:c1935960-1935901 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References