Detailed information of TA system TA072723

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1935778..1935960
• Replicon: chromosome
• Accession: NZ_CP019590
• Organism: Staphylococcus aureus strain C2406

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: BJN19_RS15200
• Protein ID: WP_001801861.1
• Coordinates: 1935778..1935873 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1935901..1935960 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BJN19_RS09830	1931438..1932064	+	627	Protein_1843	hypothetical protein	-
BJN19_RS09835	1932105..1932449	+	345	WP_000627551.1	DUF3969 family protein	-
BJN19_RS09840	1932547..1933098	+	552	WP_000414205.1	hypothetical protein	-
BJN19_RS09845	1933316..1933957	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
BJN19_RS09850	1934071..1934256	-	186	WP_000809857.1	hypothetical protein	-
BJN19_RS09855	1934258..1934434	-	177	WP_000375476.1	hypothetical protein	-
BJN19_RS09860	1934445..1934828	-	384	WP_000070811.1	hypothetical protein	-
BJN19_RS09870	1935432..1935575	-	144	WP_001549059.1	transposase	-
BJN19_RS15200	1935778..1935873	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1935901..1935960	-	60	-	-	Antitoxin
BJN19_RS09875	1935996..1936097	+	102	WP_001791893.1	hypothetical protein	-
BJN19_RS09880	1936075..1936251	-	177	Protein_1853	transposase	-
BJN19_RS09885	1936445..1936822	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA	1905413..2010519	105106

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T72723 WP_001801861.1 NZ_CP019590:1935778-1935873 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T72723 NZ_CP019590:1935778-1935873 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT72723 NZ_CP019590:c1935960-1935901 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin