72700

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2498691..2498875 Replicon chromosome
Accession NZ_CP019574
Organism Staphylococcus aureus strain USA400-0051

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag SAU400_RS13085 Protein ID WP_000482647.1
Coordinates 2498768..2498875 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2498691..2498751 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAU400_RS13060 2494165..2494332 - 168 WP_001793334.1 hypothetical protein -
SAU400_RS13070 2494563..2496296 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
SAU400_RS13075 2496321..2498084 - 1764 WP_001064815.1 ABC transporter ATP-binding protein/permease -
- 2498691..2498751 + 61 - - Antitoxin
SAU400_RS13085 2498768..2498875 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
SAU400_RS13090 2499009..2499395 - 387 WP_000779360.1 flippase GtxA -
SAU400_RS13095 2499653..2500795 + 1143 WP_001176871.1 glycerate kinase -
SAU400_RS13100 2500855..2501514 + 660 WP_000831301.1 membrane protein -
SAU400_RS13105 2501696..2502907 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
SAU400_RS13110 2503030..2503503 - 474 WP_000456497.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T72700 WP_000482647.1 NZ_CP019574:c2498875-2498768 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T72700 NZ_CP019574:c2498875-2498768 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT72700 NZ_CP019574:2498691-2498751 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References