Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2220438..2220654 Replicon chromosome
Accession NZ_CP019574
Organism Staphylococcus aureus strain USA400-0051

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SAU400_RS11565 Protein ID WP_001802298.1
Coordinates 2220550..2220654 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2220438..2220493 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAU400_RS11545 2216641..2217306 - 666 WP_001024095.1 SDR family oxidoreductase -
SAU400_RS11550 2217458..2217778 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SAU400_RS11555 2217780..2218760 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
SAU400_RS11560 2219026..2220117 + 1092 WP_000495683.1 hypothetical protein -
- 2220438..2220493 + 56 - - Antitoxin
SAU400_RS11565 2220550..2220654 - 105 WP_001802298.1 hypothetical protein Toxin
SAU400_RS11575 2221334..2221492 + 159 WP_001792784.1 hypothetical protein -
SAU400_RS11585 2222151..2223008 - 858 WP_000370917.1 Cof-type HAD-IIB family hydrolase -
SAU400_RS11590 2223076..2223858 - 783 WP_000908178.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T72696 WP_001802298.1 NZ_CP019574:c2220654-2220550 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T72696 NZ_CP019574:c2220654-2220550 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT72696 NZ_CP019574:2220438-2220493 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References