72673

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2680506..2680784 Replicon chromosome
Accession NZ_CP019563
Organism Staphylococcus aureus strain SR434

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag BZP34_RS13985 Protein ID WP_001802298.1
Coordinates 2680506..2680610 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2680606..2680784 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BZP34_RS13960 2677303..2678085 + 783 WP_000908185.1 ABC transporter ATP-binding protein -
BZP34_RS13965 2678153..2679010 + 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
BZP34_RS13975 2679668..2679826 - 159 WP_001792784.1 hypothetical protein -
BZP34_RS13985 2680506..2680610 + 105 WP_001802298.1 hypothetical protein Toxin
- 2680606..2680784 - 179 - - Antitoxin
BZP34_RS13990 2681043..2682134 - 1092 WP_000495669.1 hypothetical protein -
BZP34_RS13995 2682400..2683377 - 978 WP_000019733.1 CDF family zinc efflux transporter CzrB -
BZP34_RS14000 2683379..2683699 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
BZP34_RS14005 2683851..2684516 + 666 WP_001024089.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(6-99)


Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T72673 WP_001802298.1 NZ_CP019563:2680506-2680610 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T72673 NZ_CP019563:2680506-2680610 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 179 bp

>AT72673 NZ_CP019563:c2680784-2680606 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References