Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2399482..2399666 Replicon chromosome
Accession NZ_CP019563
Organism Staphylococcus aureus strain SR434

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag BZP34_RS12440 Protein ID WP_000482647.1
Coordinates 2399482..2399589 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2399606..2399666 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BZP34_RS12415 2394854..2395327 + 474 WP_000456489.1 GyrI-like domain-containing protein -
BZP34_RS12420 2395450..2396661 - 1212 WP_001192075.1 multidrug effflux MFS transporter -
BZP34_RS12425 2396843..2397502 - 660 WP_000831298.1 membrane protein -
BZP34_RS12430 2397562..2398704 - 1143 WP_072519225.1 glycerate kinase -
BZP34_RS12435 2398962..2399348 + 387 WP_000779347.1 flippase GtxA -
BZP34_RS12440 2399482..2399589 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2399606..2399666 - 61 - - Antitoxin
BZP34_RS12455 2400217..2401980 + 1764 WP_001064816.1 ABC transporter ATP-binding protein/permease -
BZP34_RS12460 2402005..2403738 + 1734 WP_077156124.1 ABC transporter ATP-binding protein/permease -
BZP34_RS12470 2403969..2404136 + 168 WP_001792506.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T72670 WP_000482647.1 NZ_CP019563:2399482-2399589 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T72670 NZ_CP019563:2399482-2399589 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT72670 NZ_CP019563:c2399666-2399606 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References