Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-RNAII/-
Location 2991958..2992209 Replicon chromosome
Accession NZ_CP019512
Organism Enterococcus faecalis strain CLB21560

Toxin (Protein)


Gene name txpA Uniprot ID S4BWW4
Locus tag BZG32_RS15605 Protein ID WP_002404776.1
Coordinates 2991958..2992080 (+) Length 41 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 2992146..2992209 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BZG32_RS15585 2987589..2988221 - 633 WP_002358972.1 RloB family protein -
BZG32_RS15590 2988230..2989525 - 1296 WP_002396787.1 AAA family ATPase -
BZG32_RS15600 2989987..2991603 + 1617 WP_002358967.1 phosphatase PAP2/LCP family protein -
BZG32_RS15605 2991958..2992080 + 123 WP_002404776.1 putative holin-like toxin Toxin
- 2992146..2992209 - 64 - - Antitoxin
BZG32_RS15610 2992266..2992463 + 198 WP_002358966.1 putative holin-like toxin -
BZG32_RS15615 2992582..2992722 + 141 WP_077143780.1 putative holin-like toxin -
BZG32_RS15620 2992953..2993096 + 144 WP_002396786.1 putative holin-like toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(7-40)


Sequences

Toxin        


Download         Length: 41 a.a.        Molecular weight: 4396.44 Da        Isoelectric Point: 10.2826

>T72589 WP_002404776.1 NZ_CP019512:2991958-2992080 [Enterococcus faecalis]
MKGVGLLSAYETIQTILGFGMFTIALIALIVKLLKEDKKK

Download         Length: 123 bp

>T72589 NZ_CP019512:2991958-2992080 [Enterococcus faecalis]
ATGAAAGGAGTAGGCCTTTTGTCAGCATATGAGACAATTCAGACGATCCTAGGGTTTGGTATGTTTACCATTGCTTTGAT
TGCACTGATTGTGAAATTGCTTAAAGAAGACAAAAAGAAATGA

Antitoxin


Download         Length: 64 bp

>AT72589 NZ_CP019512:c2992209-2992146 [Enterococcus faecalis]
TTGTGCTATAATAGCAATGAAAAGAGAGATATGCTGTAACATACCTCTCTAGTGTAGAGCCGTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S4BWW4

Antitoxin

Download structure file

References