Detailed information of TA system TA072575

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mqsRA (relBE)/MqsR-MqsA
• Location: 3628327..3629033
• Replicon: chromosome
• Accession: NZ_CP019509
• Organism: Aquaspirillum sp. LM1

Toxin (Protein)

• Gene name: mqsR
• Uniprot ID: -
• Locus tag: BXU06_RS15720
• Protein ID: WP_077301753.1
• Coordinates: 3628327..3628629 (+)
• Length: 101 a.a.

Antitoxin (Protein)

• Gene name: mqsA
• Uniprot ID: -
• Locus tag: BXU06_RS15725
• Protein ID: WP_077301756.1
• Coordinates: 3628632..3629033 (+)
• Length: 134 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BXU06_RS15710	3626995..3627969	-	975	WP_077301747.1	Rpn family recombination-promoting nuclease/putative transposase	-
BXU06_RS15720	3628327..3628629	+	303	WP_077301753.1	type II toxin-antitoxin system MqsR family toxin	Toxin
BXU06_RS15725	3628632..3629033	+	402	WP_077301756.1	type II toxin-antitoxin system MqsA family antitoxin	Antitoxin
BXU06_RS15730	3629209..3630522	-	1314	WP_077301759.1	FecR family protein	-
BXU06_RS15735	3630680..3631948	+	1269	WP_077301762.1	tetratricopeptide repeat protein	-
BXU06_RS15740	3632023..3633075	+	1053	WP_077301765.1	Rpn family recombination-promoting nuclease/putative transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	3602467..3637052	34585

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase toxin MqsR (6-99)

Antitoxin

• Cro/C1-type helix-turn-helix domain (74-127)

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 11073.96 Da
• Isoelectric Point: 9.1028

>T72575 WP_077301753.1 NZ_CP019509:3628327-3628629 [Aquaspirillum sp. LM1]
MEKSIPHNKLHVVKALIKAGQVRATATAFCGARELGINNLAGMCAVVKALTSADFYKSMTTHADHRIWQDVYRTRLAGEA
EVYLKLTVIDDLLVVSFKEL

Nucleotide

• Length: 303 bp

>T72575 NZ_CP019509:3628327-3628629 [Aquaspirillum sp. LM1]
ATGGAAAAAAGCATTCCGCACAACAAGTTGCATGTGGTCAAGGCATTGATCAAGGCCGGTCAGGTCAGAGCCACGGCTAC
CGCGTTTTGTGGAGCGCGTGAGCTGGGTATCAACAACTTGGCAGGGATGTGCGCAGTGGTGAAGGCGCTTACTTCCGCTG
ATTTCTACAAAAGCATGACCACTCACGCCGACCACCGTATTTGGCAAGATGTGTACCGCACTCGGTTAGCGGGCGAAGCT
GAGGTGTACCTAAAGTTGACAGTGATTGATGACTTGCTGGTTGTTTCGTTCAAGGAGCTTTAA

Antitoxin

Protein

• Length: 134 a.a.
• Molecular weight: 14904.09 Da
• Isoelectric Point: 7.1886

>AT72575 WP_077301756.1 NZ_CP019509:3628632-3629033 [Aquaspirillum sp. LM1]
MKCPVCGAVELIHDTRDISYAYKGESTMIPAVTGEFCPACGEVVLNREHGDRYSEMIGVFQRQVNSAFVDPGYITRVRRK
LDLDQRQAAELFGGGVNAFSRYENGKTKPPLALVKLFKLLDRHPDLLDELRAT

Nucleotide

• Length: 402 bp

>AT72575 NZ_CP019509:3628632-3629033 [Aquaspirillum sp. LM1]
ATGAAATGTCCTGTATGCGGCGCGGTTGAGTTGATTCACGATACGCGCGACATTTCCTATGCCTACAAGGGCGAATCCAC
CATGATCCCTGCGGTGACGGGCGAGTTCTGCCCTGCGTGTGGCGAAGTTGTTCTGAACCGCGAGCACGGCGATCGTTATA
GTGAAATGATTGGTGTATTCCAGCGACAGGTGAATTCGGCATTCGTCGATCCTGGCTATATCACCCGGGTGCGTAGAAAA
CTTGATCTCGATCAGCGTCAGGCAGCCGAACTCTTTGGCGGTGGTGTGAATGCGTTTTCACGCTACGAAAACGGCAAGAC
CAAGCCACCGCTGGCTTTGGTCAAGCTGTTCAAACTGCTAGACCGTCATCCTGATCTACTCGACGAATTGAGAGCCACCT
AA