Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_37
Location 3612554..3613184 Replicon chromosome
Accession NZ_CP019509
Organism Aquaspirillum sp. LM1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag BXU06_RS15665 Protein ID WP_077302977.1
Coordinates 3612554..3612880 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag BXU06_RS15670 Protein ID WP_077301722.1
Coordinates 3612873..3613184 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BXU06_RS15650 3608164..3609843 - 1680 WP_171982243.1 tetratricopeptide repeat protein -
BXU06_RS15655 3610446..3611396 - 951 WP_077301715.1 Rpn family recombination-promoting nuclease/putative transposase -
BXU06_RS15660 3611417..3612451 - 1035 WP_077301719.1 Rpn family recombination-promoting nuclease/putative transposase -
BXU06_RS15665 3612554..3612880 + 327 WP_077302977.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BXU06_RS15670 3612873..3613184 + 312 WP_077301722.1 helix-turn-helix transcriptional regulator Antitoxin
BXU06_RS15675 3613344..3614342 - 999 WP_077301725.1 Rpn family recombination-promoting nuclease/putative transposase -
BXU06_RS15680 3614363..3615349 - 987 WP_077301728.1 Rpn family recombination-promoting nuclease/putative transposase -
BXU06_RS15685 3615613..3615855 + 243 WP_077301731.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
BXU06_RS15690 3615852..3616193 + 342 WP_150125239.1 endoribonuclease MazF -
BXU06_RS17770 3617149..3617733 - 585 WP_171982244.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3602467..3637052 34585


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(15-103)

Antitoxin

Cro/C1-type helix-turn-helix domain

(44-97)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 12478.49 Da        Isoelectric Point: 9.6048

>T72573 WP_077302977.1 NZ_CP019509:3612554-3612880 [Aquaspirillum sp. LM1]
MNWSINYFNERVQREIAEWPVGIYADFLRLVSLMENHGADLRLPHSRAMGEGLFELRCKGSEGIGRAFYCTMVGHQIVIL
HSFIKKTPETPAHELKTARKRLKEIKHG

Download         Length: 327 bp

>T72573 NZ_CP019509:3612554-3612880 [Aquaspirillum sp. LM1]
ATGAACTGGTCAATCAATTACTTCAATGAGCGTGTCCAACGAGAAATCGCTGAATGGCCAGTGGGGATTTACGCTGACTT
TCTGCGCTTGGTGAGCCTCATGGAGAACCATGGTGCCGATCTTCGACTACCGCACTCACGGGCGATGGGCGAAGGTTTGT
TCGAGCTACGTTGCAAGGGTAGTGAAGGGATCGGCCGCGCTTTTTACTGCACGATGGTTGGTCACCAGATCGTCATTCTG
CACAGCTTCATCAAGAAAACACCGGAAACGCCAGCCCACGAACTCAAAACGGCCCGCAAGCGACTCAAGGAGATTAAACA
TGGATAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11521.06 Da        Isoelectric Point: 8.0552

>AT72573 WP_077301722.1 NZ_CP019509:3612873-3613184 [Aquaspirillum sp. LM1]
MDNDRYNPVRLDIQAELAHAMQRPGFQAAWEASEEEYAAISELLQARKEAGLTQEEVATRMGTTKSAISRLEASIRSNSH
SPSFATLRKYAHACGKRLIIKMV

Download         Length: 312 bp

>AT72573 NZ_CP019509:3612873-3613184 [Aquaspirillum sp. LM1]
ATGGATAACGACCGCTACAATCCAGTTCGCCTAGATATCCAGGCAGAACTTGCTCACGCGATGCAGCGGCCAGGCTTTCA
GGCAGCCTGGGAAGCGTCAGAAGAAGAATATGCCGCGATCAGCGAGCTGCTGCAGGCGCGCAAGGAAGCAGGGCTGACAC
AGGAAGAAGTCGCCACTCGCATGGGCACAACCAAAAGCGCCATCTCGCGTCTGGAAGCCTCAATTCGTAGCAACAGCCAT
TCCCCTTCATTCGCTACACTACGCAAATATGCACACGCCTGTGGCAAGCGGCTGATCATCAAGATGGTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References