Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HTH(antitoxin)
Location 1480362..1480947 Replicon chromosome
Accession NZ_CP019509
Organism Aquaspirillum sp. LM1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag BXU06_RS06330 Protein ID WP_077297880.1
Coordinates 1480633..1480947 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag BXU06_RS06325 Protein ID WP_077297878.1
Coordinates 1480362..1480643 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BXU06_RS06310 1475454..1478090 + 2637 WP_077297876.1 alanine--tRNA ligase -
BXU06_RS06315 1478145..1479494 - 1350 WP_077302704.1 deoxyguanosinetriphosphate triphosphohydrolase -
BXU06_RS06320 1479520..1480170 - 651 WP_077302706.1 histidine phosphatase family protein -
BXU06_RS06325 1480362..1480643 - 282 WP_077297878.1 helix-turn-helix domain-containing protein Antitoxin
BXU06_RS06330 1480633..1480947 - 315 WP_077297880.1 transcriptional regulator Toxin
BXU06_RS17320 1481094..1481447 - 354 WP_150125124.1 hypothetical protein -
BXU06_RS06335 1481583..1482806 - 1224 WP_077297882.1 IS110 family transposase -
BXU06_RS06340 1482954..1484090 + 1137 WP_077297545.1 ISAs1 family transposase -
BXU06_RS06345 1484156..1484446 + 291 WP_077297884.1 DUF4351 domain-containing protein -
BXU06_RS06350 1484454..1485200 - 747 WP_077297886.1 LytTR family DNA-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(37-81)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11622.32 Da        Isoelectric Point: 10.1782

>T72570 WP_077297880.1 NZ_CP019509:c1480947-1480633 [Aquaspirillum sp. LM1]
VRTVAETAIFQRYASEVWSEAERVEFINWIAANPEAGDVIRGSGGCRKVRWSSAGQGKRGGARVIYFNASTQTIWLLIVY
KKAKFDNLPTSFLVKLKQGVEDVI

Download         Length: 315 bp

>T72570 NZ_CP019509:c1480947-1480633 [Aquaspirillum sp. LM1]
GTGAGAACAGTTGCCGAAACCGCCATCTTTCAGCGCTATGCCAGCGAAGTCTGGTCGGAAGCCGAGCGTGTTGAATTTAT
CAACTGGATCGCCGCGAATCCCGAAGCTGGTGACGTGATCCGTGGCAGCGGTGGCTGCCGTAAGGTTCGATGGTCTTCTG
CAGGACAAGGCAAACGTGGTGGTGCTAGAGTGATTTACTTCAATGCGAGTACCCAAACAATTTGGCTCTTGATCGTCTAC
AAAAAAGCCAAGTTTGACAATCTCCCCACATCTTTCTTGGTGAAGTTGAAGCAAGGAGTTGAAGATGTCATCTGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10294.86 Da        Isoelectric Point: 10.7588

>AT72570 WP_077297878.1 NZ_CP019509:c1480643-1480362 [Aquaspirillum sp. LM1]
MSSEMQKFQSDLLESVKQMKRGEAARTTQVKLPEAAEARAKMGLSQQAFALLLGVSTRTLQDWEQGRRSPTGAAKTLLQV
AVTHPEVLRELRA

Download         Length: 282 bp

>AT72570 NZ_CP019509:c1480643-1480362 [Aquaspirillum sp. LM1]
ATGTCATCTGAAATGCAAAAATTCCAAAGTGATCTGCTTGAATCTGTCAAACAGATGAAACGCGGCGAAGCCGCCCGAAC
CACTCAAGTCAAGTTACCAGAAGCGGCTGAGGCTCGCGCCAAAATGGGCCTGTCTCAACAGGCGTTTGCTTTGCTGCTGG
GTGTCTCCACGCGTACGCTACAAGACTGGGAGCAAGGGCGCAGATCACCAACAGGTGCTGCTAAAACACTGCTTCAAGTT
GCCGTTACTCATCCTGAGGTTTTGCGTGAATTGCGTGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References