Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HTH(antitoxin)
Location 1480362..1480947 Replicon chromosome
Accession NZ_CP019509
Organism Aquaspirillum sp. LM1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag BXU06_RS06330 Protein ID WP_077297880.1
Coordinates 1480633..1480947 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag BXU06_RS06325 Protein ID WP_077297878.1
Coordinates 1480362..1480643 (-) Length 94 a.a.

Genomic Context

BXU06_RS06310BXU06_RS06340BXU06_RS06345BXU06_RS06315BXU06_RS06320BXU06_RS06325BXU06_RS06330BXU06_RS17320BXU06_RS06335BXU06_RS06350
Location: 1475454..1478090 (2637 bp)
Type: Others
Protein ID: WP_077297876.1
Location: 1482954..1484090 (1137 bp)
Type: Others
Protein ID: WP_077297545.1
Location: 1484156..1484446 (291 bp)
Type: Others
Protein ID: WP_077297884.1
Location: 1478145..1479494 (1350 bp)
Type: Others
Protein ID: WP_077302704.1
Location: 1479520..1480170 (651 bp)
Type: Others
Protein ID: WP_077302706.1
Location: 1480362..1480643 (282 bp)
Type: Antitoxin
Protein ID: WP_077297878.1
Location: 1480633..1480947 (315 bp)
Type: Toxin
Protein ID: WP_077297880.1
Location: 1481094..1481447 (354 bp)
Type: Others
Protein ID: WP_150125124.1
Location: 1481583..1482806 (1224 bp)
Type: Others
Protein ID: WP_077297882.1
Location: 1484454..1485200 (747 bp)
Type: Others
Protein ID: WP_077297886.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BXU06_RS063101475454..1478090+2637WP_077297876.1alanine--tRNA ligase-
BXU06_RS063151478145..1479494-1350WP_077302704.1deoxyguanosinetriphosphate triphosphohydrolase-
BXU06_RS063201479520..1480170-651WP_077302706.1histidine phosphatase family protein-
BXU06_RS063251480362..1480643-282WP_077297878.1helix-turn-helix domain-containing proteinAntitoxin
BXU06_RS063301480633..1480947-315WP_077297880.1transcriptional regulatorToxin
BXU06_RS173201481094..1481447-354WP_150125124.1hypothetical protein-
BXU06_RS063351481583..1482806-1224WP_077297882.1IS110 family transposase-
BXU06_RS063401482954..1484090+1137WP_077297545.1ISAs1 family transposase-
BXU06_RS063451484156..1484446+291WP_077297884.1DUF4351 domain-containing protein-
BXU06_RS063501484454..1485200-747WP_077297886.1LytTR family DNA-binding domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(37-81)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11622.32 Da        Isoelectric Point: 10.1782

>T72570 WP_077297880.1 NZ_CP019509:c1480947-1480633 [Aquaspirillum sp. LM1]
VRTVAETAIFQRYASEVWSEAERVEFINWIAANPEAGDVIRGSGGCRKVRWSSAGQGKRGGARVIYFNASTQTIWLLIVY
KKAKFDNLPTSFLVKLKQGVEDVI

Download         Length: 315 bp

>T72570 NZ_CP019509:c1480947-1480633 [Aquaspirillum sp. LM1]
GTGAGAACAGTTGCCGAAACCGCCATCTTTCAGCGCTATGCCAGCGAAGTCTGGTCGGAAGCCGAGCGTGTTGAATTTAT
CAACTGGATCGCCGCGAATCCCGAAGCTGGTGACGTGATCCGTGGCAGCGGTGGCTGCCGTAAGGTTCGATGGTCTTCTG
CAGGACAAGGCAAACGTGGTGGTGCTAGAGTGATTTACTTCAATGCGAGTACCCAAACAATTTGGCTCTTGATCGTCTAC
AAAAAAGCCAAGTTTGACAATCTCCCCACATCTTTCTTGGTGAAGTTGAAGCAAGGAGTTGAAGATGTCATCTGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10294.86 Da        Isoelectric Point: 10.7588

>AT72570 WP_077297878.1 NZ_CP019509:c1480643-1480362 [Aquaspirillum sp. LM1]
MSSEMQKFQSDLLESVKQMKRGEAARTTQVKLPEAAEARAKMGLSQQAFALLLGVSTRTLQDWEQGRRSPTGAAKTLLQV
AVTHPEVLRELRA

Download         Length: 282 bp

>AT72570 NZ_CP019509:c1480643-1480362 [Aquaspirillum sp. LM1]
ATGTCATCTGAAATGCAAAAATTCCAAAGTGATCTGCTTGAATCTGTCAAACAGATGAAACGCGGCGAAGCCGCCCGAAC
CACTCAAGTCAAGTTACCAGAAGCGGCTGAGGCTCGCGCCAAAATGGGCCTGTCTCAACAGGCGTTTGCTTTGCTGCTGG
GTGTCTCCACGCGTACGCTACAAGACTGGGAGCAAGGGCGCAGATCACCAACAGGTGCTGCTAAAACACTGCTTCAAGTT
GCCGTTACTCATCCTGAGGTTTTGCGTGAATTGCGTGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References