Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 1622683..1622905 Replicon chromosome
Accession NZ_CP019455
Organism Escherichia coli strain FHI_NMBU_03

Toxin (Protein)


Gene name ldrD Uniprot ID A0A0D6GD35
Locus tag BXO92_RS24835 Protein ID WP_000170745.1
Coordinates 1622683..1622790 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 1622847..1622905 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BXO92_RS08175 1617736..1617924 - 189 WP_001063314.1 YhjR family protein -
BXO92_RS08180 1618197..1619768 + 1572 WP_001204945.1 cellulose biosynthesis protein BcsE -
BXO92_RS08185 1619765..1619956 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
BXO92_RS08190 1619953..1621632 + 1680 WP_024223715.1 cellulose biosynthesis protein BcsG -
BXO92_RS08195 1621718..1621825 - 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
BXO92_RS24830 1622201..1622308 - 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
BXO92_RS24835 1622683..1622790 - 108 WP_000170745.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
- 1622847..1622905 + 59 - - Antitoxin
BXO92_RS08225 1623266..1624537 + 1272 WP_014640225.1 amino acid permease -
BXO92_RS08230 1624567..1625571 - 1005 WP_000103579.1 dipeptide ABC transporter ATP-binding subunit DppF -
BXO92_RS08235 1625568..1626551 - 984 WP_001196477.1 dipeptide ABC transporter ATP-binding protein -
BXO92_RS08240 1626562..1627464 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3855.68 Da        Isoelectric Point: 9.0157

>T72482 WP_000170745.1 NZ_CP019455:c1622790-1622683 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVSWLNKRK

Download         Length: 108 bp

>T72482 NZ_CP019455:c1622790-1622683 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAGCTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 59 bp

>AT72482 NZ_CP019455:1622847-1622905 [Escherichia coli]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0D6GD35

Antitoxin

Download structure file

References