Detailed information of TA system TA072480

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 1622201..1622423
• Replicon: chromosome
• Accession: NZ_CP019455
• Organism: Escherichia coli strain FHI_NMBU_03

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: S1NWX0
• Locus tag: BXO92_RS24830
• Protein ID: WP_001295224.1
• Coordinates: 1622201..1622308 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	1622357..1622423 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BXO92_RS08175	1617736..1617924	-	189	WP_001063314.1	YhjR family protein	-
BXO92_RS08180	1618197..1619768	+	1572	WP_001204945.1	cellulose biosynthesis protein BcsE	-
BXO92_RS08185	1619765..1619956	+	192	WP_000988308.1	cellulose biosynthesis protein BcsF	-
BXO92_RS08190	1619953..1621632	+	1680	WP_024223715.1	cellulose biosynthesis protein BcsG	-
BXO92_RS08195	1621718..1621825	-	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
BXO92_RS24830	1622201..1622308	-	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
-	1622357..1622423	+	67	-	-	Antitoxin
BXO92_RS24835	1622683..1622790	-	108	WP_000170745.1	type I toxin-antitoxin system toxin Ldr family protein	-
BXO92_RS08225	1623266..1624537	+	1272	WP_014640225.1	amino acid permease	-
BXO92_RS08230	1624567..1625571	-	1005	WP_000103579.1	dipeptide ABC transporter ATP-binding subunit DppF	-
BXO92_RS08235	1625568..1626551	-	984	WP_001196477.1	dipeptide ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3882.70 Da
• Isoelectric Point: 9.0157

>T72480 WP_001295224.1 NZ_CP019455:c1622308-1622201 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Nucleotide

• Length: 108 bp

>T72480 NZ_CP019455:c1622308-1622201 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCACGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin

Nucleotide

• Length: 67 bp

>AT72480 NZ_CP019455:1622357-1622423 [Escherichia coli]
GTCTAGATGCAAGAATGGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A4P7TSJ7

Antitoxin