72451

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 5470693..5471348 Replicon chromosome
Accession NZ_CP019432
Organism Pseudomonas sp. S49

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PspS49_RS24040 Protein ID WP_160041742.1
Coordinates 5471004..5471348 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PspS49_RS24035 Protein ID WP_127929687.1
Coordinates 5470693..5471007 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PspS49_RS24010 5466267..5467439 - 1173 WP_150776144.1 aspartate aminotransferase family protein -
PspS49_RS24015 5467542..5468447 + 906 WP_160041738.1 LysR family transcriptional regulator -
PspS49_RS24020 5468502..5468906 + 405 WP_160041740.1 GNAT family N-acetyltransferase -
PspS49_RS24025 5469040..5469741 + 702 WP_007949995.1 hypothetical protein -
PspS49_RS24030 5470001..5470492 - 492 WP_007916938.1 RidA family protein -
PspS49_RS24035 5470693..5471007 - 315 WP_127929687.1 helix-turn-helix domain-containing protein Antitoxin
PspS49_RS24040 5471004..5471348 - 345 WP_160041742.1 toxin Toxin
PspS49_RS24045 5471464..5472351 - 888 WP_053123579.1 heme o synthase -
PspS49_RS24050 5472362..5472697 - 336 WP_127929689.1 cytochrome o ubiquinol oxidase subunit IV -
PspS49_RS24055 5472697..5473320 - 624 WP_003227982.1 cytochrome o ubiquinol oxidase subunit III -
PspS49_RS24060 5473324..5475354 - 2031 WP_042560959.1 cytochrome o ubiquinol oxidase subunit I -
PspS49_RS24065 5475358..5476299 - 942 WP_007916947.1 ubiquinol oxidase subunit II -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(42-94)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13374.23 Da        Isoelectric Point: 8.3394

>T72451 WP_160041742.1 NZ_CP019432:c5471348-5471004 [Pseudomonas sp. S49]
MRTVFFETTIFTTSVGQYLTDDEYRELQAYMQGNPLAGDMMPRTGGFRKLRWADARRGKGRRGGLRVIYYWLMNDGQFWM
FAIYDKDELENLTAEQEKALKKAIDEELKTRGTP

Download         Length: 345 bp

>T72451 NZ_CP019432:c5471348-5471004 [Pseudomonas sp. S49]
ATGCGAACCGTATTCTTTGAAACAACGATATTTACCACGAGCGTTGGTCAGTACCTGACAGACGATGAGTACCGAGAACT
GCAGGCTTATATGCAGGGCAATCCGTTGGCAGGCGATATGATGCCCCGAACGGGTGGATTCAGAAAACTACGTTGGGCTG
ATGCTCGACGTGGCAAGGGCCGACGAGGCGGCTTGCGGGTCATCTATTATTGGCTTATGAATGATGGTCAGTTCTGGATG
TTTGCAATTTACGACAAGGATGAGCTTGAGAATCTGACTGCCGAGCAAGAAAAGGCGCTCAAAAAAGCCATAGATGAAGA
GTTGAAAACACGAGGTACCCCATGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11813.79 Da        Isoelectric Point: 10.2425

>AT72451 WP_127929687.1 NZ_CP019432:c5471007-5470693 [Pseudomonas sp. S49]
MKKRDLFAELMQGVDEMAAQREGKITLRNTVLEDKPVPEVGAQEIVALREKLHMSQAVFAKRIRASPSTLRNWEQEKSKP
NAQAALLIRLVEKFPDMVDRLSAV

Download         Length: 315 bp

>AT72451 NZ_CP019432:c5471007-5470693 [Pseudomonas sp. S49]
ATGAAAAAACGCGACCTGTTTGCAGAGTTGATGCAGGGCGTTGATGAGATGGCGGCTCAACGCGAAGGAAAAATTACCCT
GCGCAATACAGTGCTTGAGGACAAACCAGTCCCGGAAGTCGGAGCCCAAGAAATCGTGGCTTTGAGAGAAAAGTTACATA
TGTCTCAAGCCGTCTTTGCCAAGCGAATCAGGGCGAGTCCCAGCACTCTGAGAAACTGGGAGCAGGAAAAGTCAAAGCCA
AATGCTCAAGCTGCTTTGTTGATCCGTTTGGTTGAAAAATTCCCTGACATGGTTGACCGCCTGAGCGCCGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References