72436

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4144281..4144935 Replicon chromosome
Accession NZ_CP019428
Organism Pseudomonas sp. R76

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PspR76_RS18475 Protein ID WP_159957548.1
Coordinates 4144281..4144631 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PspR76_RS18480 Protein ID WP_159957550.1
Coordinates 4144621..4144935 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PspR76_RS18465 4139731..4141194 + 1464 WP_106579876.1 NADH-quinone oxidoreductase subunit NuoN -
PspR76_RS18470 4142451..4144046 + 1596 WP_159957546.1 gamma-glutamyltransferase family protein -
PspR76_RS18475 4144281..4144631 + 351 WP_159957548.1 toxin Toxin
PspR76_RS18480 4144621..4144935 + 315 WP_159957550.1 transcriptional regulator Antitoxin
PspR76_RS31130 4145145..4145705 - 561 WP_194241059.1 hypothetical protein -
PspR76_RS18490 4145850..4146602 - 753 WP_159957552.1 outer membrane beta-barrel protein -
PspR76_RS18495 4146727..4147560 - 834 WP_159957554.1 arylamine N-acetyltransferase -
PspR76_RS18500 4147681..4147917 + 237 WP_159957556.1 hypothetical protein -
PspR76_RS18505 4147964..4148164 - 201 WP_159957558.1 hypothetical protein -
PspR76_RS31085 4148179..4148355 - 177 WP_174245638.1 hypothetical protein -
PspR76_RS18510 4148483..4149004 + 522 WP_159957560.1 DUF3087 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13712.59 Da        Isoelectric Point: 9.7549

>T72436 WP_159957548.1 NZ_CP019428:4144281-4144631 [Pseudomonas sp. R76]
MDALFIELPAFERHRKDYLSDALFQGFQQELMRNPEAGDVIEGTGGLRKVRFVDERRNKGKRGGLRVIYYWWSGGTQFWL
FTLYGKHEQDDLAPHHKKALKHLLDREIKARTQHET

Download         Length: 351 bp

>T72436 NZ_CP019428:4144281-4144631 [Pseudomonas sp. R76]
ATGGATGCTCTATTTATCGAACTGCCGGCCTTCGAACGGCATCGCAAGGATTATCTGAGTGACGCTCTTTTCCAAGGTTT
TCAGCAGGAGCTGATGAGAAACCCGGAAGCGGGCGATGTCATCGAAGGGACCGGTGGGCTACGCAAGGTTCGCTTCGTTG
ATGAGCGACGCAACAAAGGCAAACGCGGTGGCCTGCGGGTCATTTATTACTGGTGGTCGGGCGGTACGCAATTCTGGCTG
TTCACCCTGTACGGCAAACACGAACAGGACGACCTGGCCCCCCATCACAAAAAAGCCCTGAAACACCTGCTGGACAGGGA
AATCAAAGCGAGAACACAACATGAAACGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11763.55 Da        Isoelectric Point: 10.4449

>AT72436 WP_159957550.1 NZ_CP019428:4144621-4144935 [Pseudomonas sp. R76]
MKREIFSELVESFDALADERQGKVTLRTHKVQLNNLAPLTAEEVVAVRQQLNLSRSVFAMYLRTNLRTLENWEQGRAKPN
AQATTLIRLVARFPETVAQLAALG

Download         Length: 315 bp

>AT72436 NZ_CP019428:4144621-4144935 [Pseudomonas sp. R76]
ATGAAACGTGAAATCTTTTCCGAACTGGTCGAAAGCTTCGACGCCCTGGCCGACGAGCGCCAAGGCAAAGTCACCCTGCG
CACCCACAAGGTCCAGCTCAACAACCTGGCCCCGCTGACCGCCGAAGAGGTGGTGGCCGTACGCCAACAGCTCAACCTGT
CCCGATCGGTGTTCGCCATGTACCTGCGCACCAACCTGCGCACCCTGGAAAACTGGGAGCAAGGTCGCGCCAAGCCGAAC
GCCCAGGCCACCACCTTGATTCGCCTGGTGGCGCGGTTTCCGGAAACCGTGGCGCAACTCGCCGCATTAGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References