Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 2063445..2063950 Replicon chromosome
Accession NZ_CP019397
Organism Pseudomonas sp. S19

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag PspS19_RS09225 Protein ID WP_159994744.1
Coordinates 2063445..2063699 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag PspS19_RS09230 Protein ID WP_159994746.1
Coordinates 2063696..2063950 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PspS19_RS09205 2058631..2059104 + 474 WP_095169293.1 MarR family transcriptional regulator -
PspS19_RS09210 2059101..2060576 + 1476 WP_159994740.1 efflux transporter outer membrane subunit -
PspS19_RS09215 2060592..2061794 + 1203 WP_159994742.1 HlyD family efflux transporter periplasmic adaptor subunit -
PspS19_RS09220 2061861..2063390 + 1530 WP_095169290.1 DHA2 family efflux MFS transporter permease subunit -
PspS19_RS09225 2063445..2063699 - 255 WP_159994744.1 Txe/YoeB family addiction module toxin Toxin
PspS19_RS09230 2063696..2063950 - 255 WP_159994746.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PspS19_RS09235 2064212..2064640 - 429 WP_159994748.1 GNAT family N-acetyltransferase -
PspS19_RS09240 2064994..2065182 + 189 WP_159994750.1 SPOR domain-containing protein -
PspS19_RS09245 2065282..2065464 - 183 WP_095169287.1 hypothetical protein -
PspS19_RS09250 2065561..2066277 - 717 WP_159994752.1 SOS response-associated peptidase family protein -
PspS19_RS09255 2066423..2066872 + 450 WP_095169285.1 GNAT family N-acetyltransferase -
PspS19_RS09260 2066884..2067531 - 648 WP_159987306.1 SOS response-associated peptidase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9967.49 Da        Isoelectric Point: 8.9271

>T72397 WP_159994744.1 NZ_CP019397:c2063699-2063445 [Pseudomonas sp. S19]
MTIVFTPQAWEDYLWFQQNDKAGLKRINLLIKATQREPFSGPGKPEPLKHNLSGFWSRRITAEHRLVYAMEGDELQIVMC
RYHY

Download         Length: 255 bp

>T72397 NZ_CP019397:c2063699-2063445 [Pseudomonas sp. S19]
ATGACGATTGTGTTCACCCCTCAAGCCTGGGAGGACTACCTCTGGTTTCAGCAGAACGACAAAGCCGGGCTGAAGCGGAT
CAACCTGTTGATCAAGGCGACTCAGCGAGAGCCCTTTAGCGGACCAGGCAAACCCGAACCGCTCAAGCATAACCTGAGCG
GATTCTGGTCCCGCAGGATCACGGCCGAACACCGTCTCGTATACGCCATGGAGGGCGACGAGTTACAGATCGTGATGTGC
CGCTACCACTACTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9530.92 Da        Isoelectric Point: 7.0130

>AT72397 WP_159994746.1 NZ_CP019397:c2063950-2063696 [Pseudomonas sp. S19]
METINYTNARAHLAETMDRVNEDRAPLLVTRQKGEPVVMMSLAEYNALEETAYLLRTPANAERLIKSINSLRAGKAKTRQ
LIEE

Download         Length: 255 bp

>AT72397 NZ_CP019397:c2063950-2063696 [Pseudomonas sp. S19]
ATGGAAACCATCAACTACACAAACGCCAGGGCTCACCTGGCAGAAACCATGGACAGAGTCAACGAGGATCGCGCGCCCCT
ACTGGTAACACGACAGAAAGGTGAGCCCGTGGTGATGATGTCGCTGGCCGAATATAACGCCCTGGAAGAAACCGCCTATC
TGCTGCGCACCCCGGCCAATGCCGAACGCCTGATCAAATCGATCAACAGTTTGCGAGCGGGCAAAGCCAAGACCAGGCAG
CTCATTGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References