Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HTH(antitoxin)
Location 4270862..4271450 Replicon chromosome
Accession NZ_CP019343
Organism Oceanicoccus sagamiensis strain NBRC 107125

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag BST96_RS19410 Protein ID WP_085760277.1
Coordinates 4271130..4271450 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag BST96_RS19405 Protein ID WP_085760276.1
Coordinates 4270862..4271137 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BST96_RS19385 4265911..4266324 - 414 WP_085760272.1 PilZ domain-containing protein -
BST96_RS19390 4266445..4268307 - 1863 WP_085760273.1 beta-ketoacyl synthase -
BST96_RS19395 4268452..4269438 + 987 WP_085760274.1 helix-turn-helix domain-containing protein -
BST96_RS19400 4269546..4270847 + 1302 WP_085760275.1 hypothetical protein -
BST96_RS19405 4270862..4271137 - 276 WP_085760276.1 helix-turn-helix domain-containing protein Antitoxin
BST96_RS19410 4271130..4271450 - 321 WP_085760277.1 transcriptional regulator Toxin
BST96_RS19415 4271520..4272887 - 1368 WP_085760278.1 cysteine--tRNA ligase -
BST96_RS19420 4272904..4273380 - 477 WP_085760279.1 YiiD C-terminal domain-containing protein -
BST96_RS19425 4273393..4274349 - 957 WP_085760280.1 methylmalonyl Co-A mutase-associated GTPase MeaB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(38-89)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12614.57 Da        Isoelectric Point: 9.4434

>T72264 WP_085760277.1 NZ_CP019343:c4271450-4271130 [Oceanicoccus sagamiensis]
MDVIEIPHFTDVVASYLSDDEYAALQWYLLLNPDAGDLIQGTGGIRKVRWFTSWYGKRGGLRVIYYYRRKPMEIWMLTVY
SKSKKQDLTTRDKEVLKQIVREIKYD

Download         Length: 321 bp

>T72264 NZ_CP019343:c4271450-4271130 [Oceanicoccus sagamiensis]
ATGGATGTTATTGAGATACCTCACTTCACGGATGTTGTGGCCAGCTATTTATCGGATGATGAATATGCTGCTTTGCAATG
GTATTTACTGTTAAACCCTGATGCAGGCGATTTGATACAGGGTACGGGTGGTATCCGAAAAGTCAGGTGGTTTACTTCCT
GGTACGGCAAACGGGGAGGTTTAAGGGTTATTTACTATTACCGGCGTAAACCCATGGAAATTTGGATGTTAACCGTTTAT
TCAAAATCAAAAAAACAAGACCTGACCACTAGGGATAAGGAGGTTTTGAAGCAGATCGTACGGGAGATAAAATATGACTG
A

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10420.03 Da        Isoelectric Point: 8.7884

>AT72264 WP_085760276.1 NZ_CP019343:c4271137-4270862 [Oceanicoccus sagamiensis]
MTDLEIDLEKQLKAIREHKTDLSKLRTHKLQDPVPPAEIRERLGLSQDAFAALLNISVKTLRNWEQGQRSPQGPALALLR
IIDRNPEVLFN

Download         Length: 276 bp

>AT72264 NZ_CP019343:c4271137-4270862 [Oceanicoccus sagamiensis]
ATGACTGATTTAGAGATAGATCTTGAGAAACAGTTAAAAGCTATTCGCGAGCATAAAACAGACCTTAGCAAGCTCCGCAC
GCACAAACTGCAGGACCCGGTGCCCCCGGCCGAGATAAGAGAGCGCCTTGGTTTGTCGCAAGATGCATTTGCGGCGCTAT
TAAATATTTCAGTAAAAACTTTGCGCAATTGGGAGCAGGGGCAGCGCTCACCACAAGGCCCAGCCCTGGCTCTACTGCGA
ATTATTGACCGCAACCCTGAAGTCTTATTTAACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References