Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-DinJ
Location 1110270..1110801 Replicon chromosome
Accession NZ_CP019323
Organism Companilactobacillus allii strain WiKim39

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag BTM29_RS05295 Protein ID WP_076614513.1
Coordinates 1110517..1110801 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag BTM29_RS05290 Protein ID WP_076614512.1
Coordinates 1110270..1110524 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BTM29_RS05270 1105706..1106989 + 1284 WP_076614508.1 Fe-S cluster assembly protein SufD -
BTM29_RS05275 1106976..1108193 + 1218 WP_076614509.1 cysteine desulfurase -
BTM29_RS05280 1108180..1108617 + 438 WP_076614510.1 SUF system NifU family Fe-S cluster assembly protein -
BTM29_RS05285 1108631..1110073 + 1443 WP_076614511.1 Fe-S cluster assembly protein SufB -
BTM29_RS05290 1110270..1110524 + 255 WP_076614512.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
BTM29_RS05295 1110517..1110801 + 285 WP_076614513.1 type II toxin-antitoxin system YafQ family toxin Toxin
BTM29_RS05300 1111025..1113361 - 2337 WP_076614514.1 HAD-IC family P-type ATPase -
BTM29_RS05305 1113441..1114103 + 663 WP_076614515.1 HAD hydrolase-like protein -
BTM29_RS05310 1114110..1114928 + 819 WP_076614516.1 hypothetical protein -
BTM29_RS05315 1114944..1115309 + 366 WP_076614517.1 iron-sulfur cluster biosynthesis family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-82)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11052.17 Da        Isoelectric Point: 10.6282

>T72249 WP_076614513.1 NZ_CP019323:1110517-1110801 [Companilactobacillus allii]
MLEIVQTPTFVKDFKKLKKKHYNMLLLKKVVTHIVKGENEILVSKYRDHALKGNWQGFREVHIEKDWLLVYLVNKGELRL
ALIRTGSHSQILGK

Download         Length: 285 bp

>T72249 NZ_CP019323:1110517-1110801 [Companilactobacillus allii]
ATGCTTGAGATTGTTCAGACCCCAACATTTGTAAAAGATTTTAAAAAATTGAAAAAGAAACATTATAATATGCTTCTACT
AAAAAAAGTAGTTACTCATATTGTAAAAGGTGAAAATGAAATATTAGTTTCAAAATATCGTGATCATGCGCTAAAAGGTA
ATTGGCAAGGATTTAGAGAAGTACATATCGAAAAGGATTGGTTATTAGTTTATTTGGTAAATAAGGGAGAGTTAAGACTG
GCCTTAATTAGAACTGGTTCCCACAGTCAAATATTAGGAAAGTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9779.07 Da        Isoelectric Point: 4.6722

>AT72249 WP_076614512.1 NZ_CP019323:1110270-1110524 [Companilactobacillus allii]
MSDTRISLRIDPELKKDAQELYSDLGLDLTSAVTMFLKQSVREQALPFKPELEDSESVQARKEAFKKDLKKYKTVDDWWD
NLNA

Download         Length: 255 bp

>AT72249 NZ_CP019323:1110270-1110524 [Companilactobacillus allii]
ATGTCTGATACCAGAATTAGTTTACGAATTGATCCGGAATTAAAAAAGGATGCACAAGAGCTATACAGTGACTTAGGTTT
GGATTTAACTTCAGCTGTAACAATGTTCTTGAAACAGTCAGTAAGAGAACAGGCGTTGCCATTTAAACCGGAATTGGAAG
ATTCCGAGAGTGTACAGGCTAGAAAAGAAGCGTTCAAAAAAGATTTAAAGAAGTATAAAACAGTTGATGATTGGTGGGAT
AATCTTAATGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References