Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 3774664..3775364 Replicon chromosome
Accession NZ_CP019240
Organism Rhodoferax antarcticus strain DSMZ24876

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag RA876_RS18315 Protein ID WP_075585425.1
Coordinates 3774664..3774960 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag RA876_RS18320 Protein ID WP_075585426.1
Coordinates 3774963..3775364 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RA876_RS18290 3770852..3771226 - 375 WP_075585421.1 hypothetical protein -
RA876_RS18295 3771732..3772094 - 363 WP_075585422.1 DDE-type integrase/transposase/recombinase -
RA876_RS20530 3772162..3772596 - 435 WP_139313291.1 hypothetical protein -
RA876_RS18305 3772962..3773255 - 294 WP_075585423.1 hypothetical protein -
RA876_RS18310 3773713..3774270 - 558 WP_075585424.1 hypothetical protein -
RA876_RS18315 3774664..3774960 + 297 WP_075585425.1 type II toxin-antitoxin system MqsR family toxin Toxin
RA876_RS18320 3774963..3775364 + 402 WP_075585426.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
RA876_RS18325 3775719..3776033 - 315 Protein_3586 histone protein -
RA876_RS18330 3776322..3777008 + 687 WP_156876289.1 hypothetical protein -
RA876_RS18335 3777018..3778148 - 1131 Protein_3588 IS110 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 3771732..3778172 6440


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Antitoxin MqsA/HigA-2

(1-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10869.66 Da        Isoelectric Point: 6.8674

>T71903 WP_075585425.1 NZ_CP019240:3774664-3774960 [Rhodoferax antarcticus]
MEKGTPHCKLTTVKALVDAGQVRTTHAARVGANEMGLDFISMLGVVTALMPADFYKSMTTHVDHTVWQDVYRPSTQMGDV
YLKLTVINDLLIVSFKEL

Download         Length: 297 bp

>T71903 NZ_CP019240:3774664-3774960 [Rhodoferax antarcticus]
ATGGAAAAAGGCACGCCTCATTGCAAGCTCACGACGGTTAAGGCCTTGGTTGATGCTGGTCAAGTGCGCACCACACACGC
AGCGCGAGTCGGCGCCAATGAGATGGGTCTTGATTTCATCAGCATGCTGGGGGTGGTGACAGCACTCATGCCTGCTGATT
TCTACAAGAGCATGACCACGCATGTCGATCACACGGTCTGGCAAGACGTGTACCGCCCAAGCACGCAAATGGGCGACGTG
TATTTGAAGCTGACGGTCATTAATGACCTGCTGATCGTGTCTTTCAAGGAGCTATGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14579.83 Da        Isoelectric Point: 6.4556

>AT71903 WP_075585426.1 NZ_CP019240:3774963-3775364 [Rhodoferax antarcticus]
MKCPVCGAAELIHDTRDLPYTYKGETILIAAVTGDFCPACAESILDAAQSDRVMREMRDFSKQVNAAIVDPGFITSVRKK
LSLDQREAAEIFGGGVNAFSRYENGKTKPPLALVKLLKVLERHPDLLDEVRAA

Download         Length: 402 bp

>AT71903 NZ_CP019240:3774963-3775364 [Rhodoferax antarcticus]
ATGAAATGTCCTGTATGCGGCGCAGCCGAACTGATCCATGACACCCGCGACCTGCCCTATACCTACAAGGGCGAAACCAT
TCTCATTGCGGCAGTGACGGGCGACTTCTGCCCGGCCTGTGCAGAATCGATCCTGGATGCAGCGCAATCTGATCGCGTCA
TGCGCGAAATGCGCGATTTCTCCAAGCAGGTCAATGCGGCAATCGTCGATCCTGGCTTTATCACCAGCGTGCGCAAGAAA
CTCTCTCTCGACCAGCGTGAAGCCGCCGAAATCTTCGGTGGCGGAGTCAATGCCTTCTCACGGTACGAAAACGGCAAGAC
CAAACCACCGCTAGCTTTGGTGAAATTGCTCAAGGTACTGGAGCGTCACCCCGATCTGCTCGATGAGGTTAGAGCCGCCT
GA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References