Detailed information of TA system TA071880

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/Txe-RelB
• Location: 2141867..2142372
• Replicon: chromosome
• Accession: NZ_CP019229
• Organism: Tessaracoccus sp. T2.5-30

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: BKM78_RS09725
• Protein ID: WP_078919985.1
• Coordinates: 2141867..2142133 (-)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: BKM78_RS09730
• Protein ID: WP_078919986.1
• Coordinates: 2142130..2142372 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BKM78_RS09690	2137374..2137871	+	498	WP_068750332.1	hypothetical protein	-
BKM78_RS09695	2138261..2138764	+	504	WP_068750330.1	metallophosphatase family protein	-
BKM78_RS09700	2138832..2139215	+	384	WP_068750328.1	alcohol dehydrogenase	-
BKM78_RS09705	2139294..2139578	+	285	WP_188426943.1	hypothetical protein	-
BKM78_RS09710	2139662..2140054	-	393	WP_068750324.1	type II toxin-antitoxin system VapC family toxin	-
BKM78_RS09715	2140051..2140278	-	228	WP_068750322.1	antitoxin	-
BKM78_RS09720	2140361..2141599	-	1239	WP_078919578.1	IS110 family transposase	-
BKM78_RS09725	2141867..2142133	-	267	WP_078919985.1	Txe/YoeB family addiction module toxin	Toxin
BKM78_RS09730	2142130..2142372	-	243	WP_078919986.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
BKM78_RS09735	2142531..2143292	+	762	WP_078919987.1	aldo/keto reductase	-
BKM78_RS09740	2143701..2144075	+	375	WP_078919988.1	DUF2200 domain-containing protein	-
BKM78_RS09745	2144072..2144473	+	402	WP_078919989.1	hypothetical protein	-
BKM78_RS09750	2144625..2144915	+	291	WP_141679993.1	hypothetical protein	-
BKM78_RS09755	2144951..2145172	+	222	WP_078919990.1	hypothetical protein	-
BKM78_RS09760	2145284..2146495	+	1212	WP_078919991.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (9-86)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-68)

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10205.93 Da
• Isoelectric Point: 10.0709

>T71880 WP_078919985.1 NZ_CP019229:c2142133-2141867 [Tessaracoccus sp. T2.5-30]
VNSWTLVYSRQAQKDAKKLASPGLKTKAQHLLEVLAQDPFTTPPKYEKLVGALVGCYSRRINIQHRLVYEVLPERHVVHI
LRMWTHCE

Nucleotide

• Length: 267 bp

>T71880 NZ_CP019229:c2142133-2141867 [Tessaracoccus sp. T2.5-30]
GTGAACTCCTGGACTCTGGTGTACTCGCGCCAGGCCCAGAAGGACGCCAAGAAGCTGGCCTCCCCGGGGCTGAAGACGAA
GGCGCAGCACCTGTTGGAGGTCCTGGCCCAGGATCCGTTCACCACCCCACCCAAGTACGAGAAGTTGGTCGGCGCCCTCG
TGGGCTGCTACTCAAGACGCATCAATATCCAGCACCGACTTGTCTATGAGGTGCTCCCTGAGCGCCACGTCGTCCACATT
CTGAGGATGTGGACGCACTGCGAGTAG

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8716.65 Da
• Isoelectric Point: 3.9557

>AT71880 WP_078919986.1 NZ_CP019229:c2142372-2142130 [Tessaracoccus sp. T2.5-30]
MTAVNATSARANLYRLIDQVNEESEPLTITGQRGNAVLVGEEDWLAIQETLFLESVPGLAESIRRARAEGVDAGSTELDW

Nucleotide

• Length: 243 bp

>AT71880 NZ_CP019229:c2142372-2142130 [Tessaracoccus sp. T2.5-30]
ATGACTGCTGTGAACGCGACGTCTGCCCGGGCGAATCTGTACCGGTTGATCGATCAGGTCAACGAGGAGTCCGAGCCGTT
GACCATCACCGGGCAGCGTGGCAATGCTGTGCTTGTCGGCGAGGAGGACTGGCTGGCCATTCAGGAGACACTGTTCCTGG
AGTCGGTGCCTGGGTTGGCTGAGTCGATCCGTCGTGCCCGCGCGGAGGGTGTCGATGCGGGCTCGACCGAGCTGGACTGG
TGA