Detailed information of TA system TA071879

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/Txe-RelB
• Location: 1671208..1671713
• Replicon: chromosome
• Accession: NZ_CP019229
• Organism: Tessaracoccus sp. T2.5-30

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: BKM78_RS07650
• Protein ID: WP_078919878.1
• Coordinates: 1671208..1671474 (-)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: BKM78_RS07655
• Protein ID: WP_076063562.1
• Coordinates: 1671471..1671713 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BKM78_RS07630	1667069..1668028	-	960	WP_078919875.1	aldo/keto reductase	-
BKM78_RS07640	1668899..1669651	+	753	WP_078919877.1	potassium channel family protein	-
BKM78_RS07645	1669702..1670940	-	1239	WP_078919578.1	IS110 family transposase	-
BKM78_RS07650	1671208..1671474	-	267	WP_078919878.1	Txe/YoeB family addiction module toxin	Toxin
BKM78_RS07655	1671471..1671713	-	243	WP_076063562.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
BKM78_RS07660	1671899..1674217	-	2319	WP_078919879.1	pyruvate dehydrogenase	-
BKM78_RS07665	1674248..1675084	-	837	WP_078919880.1	carbohydrate ABC transporter permease	-
BKM78_RS07670	1675081..1675878	-	798	WP_078920441.1	sugar ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (8-87)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-68)

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10265.97 Da
• Isoelectric Point: 10.1636

>T71879 WP_078919878.1 NZ_CP019229:c1671474-1671208 [Tessaracoccus sp. T2.5-30]
VNSWTLVYSRQAQKDAKKLASPGLKTKAQHLLEVLAQDPFTTPPKYEKLVGALVGCYSRRINIQHRLVYEVLPERHVVHI
LRMWTHYE

Nucleotide

• Length: 267 bp

>T71879 NZ_CP019229:c1671474-1671208 [Tessaracoccus sp. T2.5-30]
GTGAACTCCTGGACTCTGGTGTACTCGCGCCAGGCCCAGAAGGACGCCAAGAAGCTGGCCTCCCCGGGGCTGAAGACGAA
GGCGCAGCACCTGTTGGAGGTCCTGGCCCAGGATCCGTTCACCACCCCACCCAAGTACGAGAAGTTGGTCGGCGCCCTCG
TGGGCTGCTACTCAAGACGCATCAATATCCAGCACCGACTTGTCTATGAGGTGCTCCCTGAGCGCCACGTCGTCCACATT
CTGAGGATGTGGACGCACTACGAGTAG

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8689.63 Da
• Isoelectric Point: 3.9557

>AT71879 WP_076063562.1 NZ_CP019229:c1671713-1671471 [Tessaracoccus sp. T2.5-30]
MTAVSATSARANLYRLIDQVNEESEPLTITGQRGNAVLVGEEDWLAIQETLFLESVPGLAESIRRARAEGVDAGSTELDW

Nucleotide

• Length: 243 bp

>AT71879 NZ_CP019229:c1671713-1671471 [Tessaracoccus sp. T2.5-30]
ATGACTGCTGTGAGCGCGACGTCTGCCCGGGCGAATCTGTACCGGTTGATTGATCAGGTCAACGAGGAGTCCGAGCCGTT
GACCATCACCGGGCAGCGTGGCAATGCTGTGCTTGTCGGCGAGGAGGACTGGCTGGCCATTCAGGAGACACTGTTCCTGG
AGTCGGTGCCTGGGTTGGCTGAGTCGATCCGTCGTGCCCGCGCGGAGGGTGTCGATGCGGGCTCGACCGAGCTGGACTGG
TGA