Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 4628853..4629442 Replicon chromosome
Accession NZ_CP019228
Organism Xanthomonas oryzae pv. oryzae strain IX-221

Toxin (Protein)


Gene name graT Uniprot ID A0A8E2YMU3
Locus tag BHL62_RS21675 Protein ID WP_011260747.1
Coordinates 4629161..4629442 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag BHL62_RS21670 Protein ID WP_011260746.1
Coordinates 4628853..4629143 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BHL62_RS21640 (BHL62_23305) 4623997..4624605 - 609 WP_011409746.1 DUF4123 domain-containing protein -
BHL62_RS21645 (BHL62_23310) 4624608..4625021 - 414 WP_228383576.1 PAAR domain-containing protein -
BHL62_RS21650 (BHL62_23315) 4625158..4625484 - 327 WP_228329596.1 hypothetical protein -
BHL62_RS21655 (BHL62_23325) 4625739..4626071 + 333 WP_011260743.1 hypothetical protein -
BHL62_RS21660 4626231..4626418 + 188 Protein_4137 hypothetical protein -
BHL62_RS21665 (BHL62_23330) 4626521..4627915 - 1395 WP_027703652.1 type III secretion system effector XopQ -
BHL62_RS21670 (BHL62_23340) 4628853..4629143 - 291 WP_011260746.1 HigA family addiction module antitoxin Antitoxin
BHL62_RS21675 (BHL62_23345) 4629161..4629442 - 282 WP_011260747.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BHL62_RS21680 (BHL62_23350) 4629537..4631789 - 2253 WP_075243583.1 exodeoxyribonuclease V subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(14-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11070.83 Da        Isoelectric Point: 10.2139

>T71876 WP_011260747.1 NZ_CP019228:c4629442-4629161 [Xanthomonas oryzae pv. oryzae]
MIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQQRGQYSIRINDQWRICFRWM
EGDVVQVEIVDYH

Download         Length: 282 bp

>T71876 NZ_CP019228:c4629442-4629161 [Xanthomonas oryzae pv. oryzae]
ATGATCAGGAGCTTTATCGACAAGGACGCCGAAAAGATCTGGCTGGGTGAGCGTTCCCGCCGGTTGCCTGCCGACATCCA
ATTGGTCGCGCGCCGCAAGTTGCGCATGCTCAATGCCGCCGCGCATCTCGACGATCTGCGGATCCCGCCCGCCAACCGGC
TGGAAGCGTTGAAGGGCCAGCAGCGCGGCCAGTACAGCATCCGGATCAACGATCAATGGCGCATCTGCTTCCGATGGATG
GAAGGCGATGTGGTCCAGGTCGAAATCGTCGATTACCACTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10420.07 Da        Isoelectric Point: 7.2040

>AT71876 WP_011260746.1 NZ_CP019228:c4629143-4628853 [Xanthomonas oryzae pv. oryzae]
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp

>AT71876 NZ_CP019228:c4629143-4628853 [Xanthomonas oryzae pv. oryzae]
ATGACGGTCCTACCCAATATCCATCCTGGCGACATTCTGCTTGAGGAGTTTCTCGAGCCTCTGGGCATCAGCCAGAACGC
ACTGGCACGCGCCACCGGCGTCCCGCCGCGCCGTATCAACGAAATCGTGCTGGGCAAGCGCGGCATCACTGCCGACACTG
CCGTGCGTCTGGCCGCCGCGTTGGGCACCTCCGAGCGCTTCTGGCTGGGCCTGCAGGCCGACTACGAGCTGGAACAGGCG
CATCGCGCGCTGGGCGATTTGCCGGCACGGATCAAGCGGCTGGCGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References