Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2208211..2208473 Replicon chromosome
Accession NZ_CP019117
Organism Staphylococcus aureus strain SJTUF_J27

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag BRL61_RS11450 Protein ID WP_073392962.1
Coordinates 2208369..2208473 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2208211..2208374 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BRL61_RS11430 2204451..2205116 - 666 WP_001024099.1 SDR family oxidoreductase -
BRL61_RS11435 2205268..2205588 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
BRL61_RS11440 2205590..2206570 + 981 WP_000019741.1 CDF family zinc efflux transporter CzrB -
BRL61_RS11445 2206836..2207927 + 1092 WP_053865863.1 hypothetical protein -
- 2208211..2208374 + 164 - - Antitoxin
BRL61_RS11450 2208369..2208473 - 105 WP_073392962.1 hypothetical protein Toxin
BRL61_RS11460 2209153..2209311 + 159 WP_001792784.1 hypothetical protein -
BRL61_RS11470 2209970..2210827 - 858 WP_000370937.1 Cof-type HAD-IIB family hydrolase -
BRL61_RS11475 2210895..2211677 - 783 WP_000908186.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T71759 WP_073392962.1 NZ_CP019117:c2208473-2208369 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T71759 NZ_CP019117:c2208473-2208369 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 164 bp

>AT71759 NZ_CP019117:2208211-2208374 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References