Detailed information of TA system TA071754

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1875740..1875920
• Replicon: chromosome
• Accession: NZ_CP019117
• Organism: Staphylococcus aureus strain SJTUF_J27

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: BRL61_RS14785
• Protein ID: WP_001801861.1
• Coordinates: 1875740..1875835 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1875863..1875920 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BRL61_RS09350	1870884..1871510	+	627	WP_000669038.1	hypothetical protein	-
BRL61_RS09355	1871551..1871895	+	345	WP_000627550.1	DUF3969 family protein	-
BRL61_RS09360	1871993..1872565	+	573	WP_000414222.1	hypothetical protein	-
BRL61_RS09365	1872714..1874081	-	1368	WP_001093574.1	FRG domain-containing protein	-
BRL61_RS09370	1874081..1874650	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
BRL61_RS09375	1874843..1875289	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
BRL61_RS14785	1875740..1875835	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1875863..1875920	-	58	-	-	Antitoxin
BRL61_RS09385	1875958..1876059	+	102	WP_001791232.1	hypothetical protein	-
BRL61_RS09390	1876234..1876677	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
BRL61_RS09395	1876677..1877120	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
BRL61_RS09400	1877120..1877562	-	443	Protein_1763	DUF1433 domain-containing protein	-
BRL61_RS09405	1878087..1880507	+	2421	WP_000182551.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T71754 WP_001801861.1 NZ_CP019117:1875740-1875835 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T71754 NZ_CP019117:1875740-1875835 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT71754 NZ_CP019117:c1875920-1875863 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin