Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 3501060..3501778 Replicon chromosome
Accession NZ_CP019062
Organism Rahnella sp. ERMR1:05

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag BV494_RS16200 Protein ID WP_104923779.1
Coordinates 3501467..3501778 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag BV494_RS16195 Protein ID WP_104923778.1
Coordinates 3501060..3501470 (-) Length 137 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BV494_RS16175 3496507..3497406 + 900 WP_192938020.1 LysR family transcriptional regulator -
BV494_RS16180 3497491..3498606 + 1116 WP_104923775.1 inner membrane protein YhjD -
BV494_RS16185 3498893..3500215 + 1323 WP_104923776.1 MHS family MFS transporter -
BV494_RS16190 3500276..3501046 + 771 WP_104923777.1 CDP-diacylglycerol diphosphatase -
BV494_RS16195 3501060..3501470 - 411 WP_104923778.1 helix-turn-helix domain-containing protein Antitoxin
BV494_RS16200 3501467..3501778 - 312 WP_104923779.1 type II toxin-antitoxin system HigB family toxin Toxin
BV494_RS16205 3501871..3503925 - 2055 WP_104923780.1 AsmA family protein -
BV494_RS16210 3504138..3504914 - 777 WP_104924820.1 cyclic-guanylate-specific phosphodiesterase -
BV494_RS16215 3505273..3506211 + 939 WP_104923781.1 sugar kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, mRNA interferase HigB

(21-93)

Antitoxin

Antitoxin HigA

(2-136)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 12033.07 Da        Isoelectric Point: 10.2763

>T71667 WP_104923779.1 NZ_CP019062:c3501778-3501467 [Rahnella sp. ERMR1:05]
MHLITMRALAEAAVRFPQYKADLLNLGKVIEKGNFPNPAALKKVYPSLDNFKYLDKHYVINIARNDVRVIALIFFESQKF
YVKGVYTHAEYDRFTDLHRGKKK

Download         Length: 312 bp

>T71667 NZ_CP019062:c3501778-3501467 [Rahnella sp. ERMR1:05]
ATGCATCTGATTACAATGCGGGCCTTAGCTGAAGCCGCAGTACGTTTTCCGCAATATAAAGCGGACTTACTGAATCTCGG
GAAGGTCATCGAGAAAGGGAATTTTCCAAACCCGGCGGCGCTTAAAAAAGTTTATCCTTCGCTGGATAACTTCAAATATC
TGGATAAACATTATGTTATCAACATCGCAAGAAACGACGTCAGAGTCATTGCGTTGATCTTCTTCGAGAGCCAGAAGTTT
TACGTTAAAGGGGTTTATACCCACGCTGAGTATGATCGTTTTACCGATTTGCACCGGGGTAAAAAGAAATGA

Antitoxin


Download         Length: 137 a.a.        Molecular weight: 14804.11 Da        Isoelectric Point: 4.4663

>AT71667 WP_104923778.1 NZ_CP019062:c3501470-3501060 [Rahnella sp. ERMR1:05]
MINEAIKATEALVSAVPLLGDNASEQDYQKALELVEYLLMNNPTSPLLDIVSNKITAYENTLPQVIAFREEMEALPGGVA
VLATLMDQYGLKQSDFADEIGGKSLVSRILRGERKLTVEHIGKLAARFGISPALFI

Download         Length: 411 bp

>AT71667 NZ_CP019062:c3501470-3501060 [Rahnella sp. ERMR1:05]
ATGATTAATGAAGCCATTAAAGCGACTGAGGCGTTGGTCAGCGCCGTACCTCTGCTGGGCGATAACGCCAGCGAGCAGGA
TTATCAGAAAGCGCTGGAACTGGTTGAGTACCTGTTGATGAACAACCCGACCAGTCCTTTACTCGATATTGTCAGCAATA
AAATCACGGCTTACGAAAATACGCTTCCGCAGGTCATCGCCTTTCGTGAAGAGATGGAAGCCCTGCCGGGCGGCGTTGCC
GTTCTTGCCACGCTGATGGATCAGTACGGCTTAAAGCAGAGTGATTTTGCCGATGAAATCGGCGGGAAATCGCTGGTGTC
GCGGATTTTACGCGGAGAACGCAAGCTGACCGTCGAACATATTGGCAAGCTTGCGGCCCGTTTTGGCATCTCTCCCGCGC
TGTTTATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References