Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 2210622..2211160 Replicon chromosome
Accession NZ_CP018911
Organism Glycocaulis alkaliphilus strain 6B-8

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag X907_RS10525 Protein ID WP_127567774.1
Coordinates 2210894..2211160 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag X907_RS10520 Protein ID WP_127569476.1
Coordinates 2210622..2210897 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
X907_RS10485 2205641..2206453 - 813 WP_170175528.1 DUF1499 domain-containing protein -
X907_RS10490 2206485..2207153 - 669 WP_127567760.1 pyridoxamine 5'-phosphate oxidase -
X907_RS10495 2207255..2207824 + 570 WP_127567762.1 J domain-containing protein -
X907_RS10500 2208055..2208642 + 588 WP_127567765.1 hypothetical protein -
X907_RS10505 2208646..2209740 + 1095 WP_127567767.1 chorismate synthase -
X907_RS10510 2209737..2210144 + 408 WP_127567769.1 NUDIX hydrolase -
X907_RS10515 2210177..2210584 + 408 WP_170175529.1 TIGR02301 family protein -
X907_RS10520 2210622..2210897 + 276 WP_127569476.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
X907_RS10525 2210894..2211160 + 267 WP_127567774.1 Txe/YoeB family addiction module toxin Toxin
X907_RS10530 2211170..2211700 + 531 WP_127567776.1 hypothetical protein -
X907_RS10535 2211704..2213236 - 1533 WP_127567778.1 acyl-CoA carboxylase subunit beta -
X907_RS10540 2213383..2214312 + 930 WP_127567780.1 FkbM family methyltransferase -
X907_RS10545 2214339..2215787 + 1449 WP_127567782.1 MBOAT family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-72)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10142.69 Da        Isoelectric Point: 9.1353

>T70806 WP_127567774.1 NZ_CP018911:2210894-2211160 [Glycocaulis alkaliphilus]
VNVELTPQALEDIGWLTAQQPKLLKRCLKLIEDIRRAPFDGLGKPEPLKGSLSGWWSRRIDGEHRLVYRVTGTGDDARIQ
IVQCRYHY

Download         Length: 267 bp

>T70806 NZ_CP018911:2210894-2211160 [Glycocaulis alkaliphilus]
GTGAATGTCGAGCTGACGCCTCAGGCCCTTGAGGATATTGGCTGGCTGACCGCCCAGCAGCCCAAACTCCTGAAACGCTG
CCTGAAACTCATCGAGGACATACGCCGTGCGCCGTTTGACGGCCTTGGCAAGCCTGAACCGCTAAAGGGCTCGCTGTCGG
GCTGGTGGTCGCGCCGCATCGATGGCGAACACCGCCTCGTCTACCGCGTCACCGGAACGGGCGACGATGCCCGCATCCAG
ATCGTGCAGTGCCGGTATCATTATTGA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9703.13 Da        Isoelectric Point: 5.8086

>AT70806 WP_127569476.1 NZ_CP018911:2210622-2210897 [Glycocaulis alkaliphilus]
MDTILTFSQARASLKALMERVTGNKAPAIITRQGGEPVVMVPLSEWEAIQETNYLLKSPANAARLAASIAAADKGEAVRH
SADELAALLDR

Download         Length: 276 bp

>AT70806 NZ_CP018911:2210622-2210897 [Glycocaulis alkaliphilus]
ATGGATACGATCCTCACCTTCAGCCAAGCGCGCGCCAGCCTGAAAGCGCTGATGGAGCGCGTCACCGGCAACAAGGCACC
GGCCATCATCACCCGTCAGGGCGGTGAGCCGGTGGTGATGGTGCCGCTGTCTGAATGGGAAGCCATTCAGGAGACGAACT
ATCTGCTCAAAAGCCCGGCCAATGCCGCGCGCCTTGCCGCCTCCATCGCCGCTGCGGACAAGGGCGAAGCCGTGCGCCAC
AGCGCCGATGAGCTTGCCGCGCTGCTGGACCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References