Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-sprA1AS/-
Location 1547625..1547773 Replicon chromosome
Accession NZ_CP018842
Organism Staphylococcus epidermidis strain 14.1.R1

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag BUM85_RS07725 Protein ID WP_011276848.1
Coordinates 1547678..1547773 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1547625..1547660 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BUM85_RS07685 1543083..1543509 - 427 Protein_1479 hypothetical protein -
BUM85_RS07690 1543553..1543813 - 261 Protein_1480 IS200/IS605 family transposase -
BUM85_RS07695 1543886..1544257 - 372 Protein_1481 recombinase family protein -
BUM85_RS07700 1544520..1545170 - 651 WP_002476158.1 NAD(P)-dependent oxidoreductase -
BUM85_RS07705 1545219..1545527 - 309 WP_002476154.1 DoxX family protein -
BUM85_RS07710 1545543..1546202 - 660 Protein_1484 DsbA family oxidoreductase -
BUM85_RS07715 1546323..1546751 - 429 WP_002476150.1 Rrf2 family transcriptional regulator -
BUM85_RS07720 1546865..1547296 - 432 Protein_1486 thymidylate synthase -
- 1547625..1547660 - 36 - - Antitoxin
BUM85_RS07725 1547678..1547773 - 96 WP_011276848.1 type I toxin-antitoxin system Fst family toxin Toxin
BUM85_RS07730 1548693..1548758 + 66 WP_109043807.1 YSIRK-type signal peptide-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1543535..1543813 278


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3623.38 Da        Isoelectric Point: 9.5124

>T70688 WP_011276848.1 NZ_CP018842:c1547773-1547678 [Staphylococcus epidermidis]
MLEILVHITTTVISGCIIALFTHWLRNRKDK

Download         Length: 96 bp

>T70688 NZ_CP018842:c1547773-1547678 [Staphylococcus epidermidis]
ATGTTGGAAATCCTTGTTCACATCACGACCACAGTCATCAGTGGTTGTATTATTGCGTTATTTACGCATTGGCTGCGTAA
TCGCAAAGACAAATAG

Antitoxin


Download         Length: 36 bp

>AT70688 NZ_CP018842:c1547660-1547625 [Staphylococcus epidermidis]
TACAAAAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References