Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 3500908..3501496 Replicon chromosome
Accession NZ_CP018756
Organism Stenotrophomonas maltophilia strain AA1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag BTU49_RS15935 Protein ID WP_079223453.1
Coordinates 3501218..3501496 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag BTU49_RS15930 Protein ID WP_079223451.1
Coordinates 3500908..3501207 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BTU49_RS15910 3496405..3497589 + 1185 WP_079223444.1 pyridoxal phosphate-dependent aminotransferase -
BTU49_RS15915 3497658..3499754 - 2097 WP_079223446.1 prolyl oligopeptidase family protein -
BTU49_RS15920 3499824..3500138 - 315 WP_079223447.1 hypothetical protein -
BTU49_RS15925 3500264..3500866 + 603 WP_079223449.1 lipocalin family protein -
BTU49_RS15930 3500908..3501207 - 300 WP_079223451.1 HigA family addiction module antidote protein Antitoxin
BTU49_RS15935 3501218..3501496 - 279 WP_079223453.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BTU49_RS15940 3501657..3502346 - 690 WP_079223454.1 ABC transporter permease -
BTU49_RS15945 3502343..3503350 - 1008 WP_079223455.1 methionine ABC transporter ATP-binding protein -
BTU49_RS15950 3503552..3504448 - 897 WP_079223457.1 DMT family transporter -
BTU49_RS15955 3504540..3505022 + 483 WP_079223459.1 YajQ family cyclic di-GMP-binding protein -
BTU49_RS15960 3505132..3506220 - 1089 WP_079223461.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(27-92)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(8-83)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10802.45 Da        Isoelectric Point: 10.2235

>T70389 WP_079223453.1 NZ_CP018756:c3501496-3501218 [Stenotrophomonas maltophilia]
MIRSFRCKHTRALFEGHCLRVWLPIRRAAERKLQMLDSAQTLAFLRSPPGNRLEALAGDRRGQHSLRINDQWRLCFIWTD
SGPESVEIVDYH

Download         Length: 279 bp

>T70389 NZ_CP018756:c3501496-3501218 [Stenotrophomonas maltophilia]
ATGATCCGGTCCTTCCGCTGCAAGCACACCCGCGCCTTGTTTGAAGGCCACTGTCTACGCGTCTGGCTGCCGATTCGACG
GGCAGCGGAACGCAAGCTGCAGATGCTCGACTCGGCACAGACGCTGGCGTTCCTGCGCAGTCCGCCCGGCAACCGGTTGG
AGGCGCTGGCTGGTGACCGCAGGGGGCAGCACAGCCTGCGCATCAATGATCAGTGGCGGTTGTGTTTCATCTGGACCGAC
AGCGGCCCTGAATCCGTGGAAATTGTTGACTACCACTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10805.43 Da        Isoelectric Point: 10.1924

>AT70389 WP_079223451.1 NZ_CP018756:c3501207-3500908 [Stenotrophomonas maltophilia]
MKPTDNRMRAIHPGEILREEFLSPLALSVNALARALDVPATRLHAIVHGERAITADTAARLARHFGGDAASWLALQATYD
LKTLATLGEIERRVQPRAA

Download         Length: 300 bp

>AT70389 NZ_CP018756:c3501207-3500908 [Stenotrophomonas maltophilia]
ATGAAGCCAACCGACAACCGCATGCGGGCCATCCATCCCGGCGAGATCCTGCGCGAGGAGTTCCTTTCCCCGCTGGCCCT
GAGCGTGAATGCACTGGCGAGGGCATTGGATGTTCCGGCCACCCGCCTGCATGCCATCGTTCACGGCGAACGTGCGATCA
CCGCTGATACCGCTGCCCGGCTGGCGCGCCATTTCGGCGGGGATGCTGCATCGTGGCTGGCGCTGCAGGCGACCTACGAC
CTGAAGACGTTGGCCACGCTTGGCGAGATCGAGCGCCGCGTGCAGCCGCGGGCCGCGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References