Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2432924..2433187 Replicon chromosome
Accession NZ_CP018629
Organism Staphylococcus aureus strain MRSA107

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag BTN44_RS13095 Protein ID WP_001802298.1
Coordinates 2433083..2433187 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2432924..2433088 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BTN44_RS13075 2429107..2429772 - 666 WP_001024094.1 SDR family oxidoreductase -
BTN44_RS13080 2429924..2430244 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
BTN44_RS13085 2430246..2431226 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
BTN44_RS13090 2431492..2432583 + 1092 WP_000495671.1 lytic regulatory protein -
- 2432924..2433088 + 165 - - Antitoxin
BTN44_RS13095 2433083..2433187 - 105 WP_001802298.1 hypothetical protein Toxin
BTN44_RS16530 2433348..2433831 - 484 Protein_2441 recombinase family protein -
BTN44_RS13105 2433874..2435010 - 1137 WP_000115564.1 SAP domain-containing protein -
BTN44_RS13110 2435299..2435391 + 93 WP_001790138.1 hypothetical protein -
BTN44_RS13115 2436096..2436953 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
BTN44_RS13120 2437021..2437803 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T70126 WP_001802298.1 NZ_CP018629:c2433187-2433083 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T70126 NZ_CP018629:c2433187-2433083 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT70126 NZ_CP018629:2432924-2433088 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References