Detailed information of TA system TA070113

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 541140..541322
• Replicon: chromosome
• Accession: NZ_CP018629
• Organism: Staphylococcus aureus strain MRSA107

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: BTN44_RS16505
• Protein ID: WP_001801861.1
• Coordinates: 541227..541322 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	541140..541199 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BTN44_RS03015	537266..538437	+	1172	Protein_534	IS256-like element IS256 family transposase	-
BTN44_RS03025	538489..539757	+	1269	Protein_535	ATP-binding protein	-
BTN44_RS03030	540278..540655	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
BTN44_RS03035	540849..541025	+	177	Protein_537	transposase	-
BTN44_RS03040	541003..541104	-	102	WP_001791893.1	hypothetical protein	-
-	541140..541199	+	60	-	-	Antitoxin
BTN44_RS16505	541227..541322	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
BTN44_RS03050	541525..541668	+	144	WP_001549059.1	transposase	-
BTN44_RS03060	542272..542655	+	384	WP_000070811.1	hypothetical protein	-
BTN44_RS03065	542666..542842	+	177	WP_000375476.1	hypothetical protein	-
BTN44_RS03070	542844..543029	+	186	WP_000809857.1	hypothetical protein	-
BTN44_RS03075	543143..543784	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
BTN44_RS03080	544002..544553	-	552	WP_000414205.1	hypothetical protein	-
BTN44_RS03085	544651..544995	-	345	WP_000627551.1	DUF3969 family protein	-
BTN44_RS03090	545036..545662	-	627	WP_000669046.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hlgA / lukD	506639..567347	60708

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-82)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T70113 WP_001801861.1 NZ_CP018629:c541322-541227 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T70113 NZ_CP018629:c541322-541227 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT70113 NZ_CP018629:541140-541199 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin