Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 1055718..1056228 Replicon chromosome
Accession NZ_CP018298
Organism Photobacterium damselae strain Phdp Wu-1

Toxin (Protein)


Gene name yoeB Uniprot ID A0A2T3QIJ8
Locus tag BST98_RS19180 Protein ID WP_036765839.1
Coordinates 1055968..1056228 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A2T3QIT0
Locus tag BST98_RS19175 Protein ID WP_036765838.1
Coordinates 1055718..1055978 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BST98_RS19150 1051249..1052013 + 765 WP_109375802.1 TPM domain-containing protein -
BST98_RS19155 1052016..1052633 + 618 WP_068968728.1 TPM domain-containing protein -
BST98_RS19160 1052809..1053027 + 219 WP_050787827.1 YgjV family protein -
BST98_RS19165 1053034..1053768 + 735 WP_109375803.1 hypothetical protein -
BST98_RS19170 1053843..1055525 + 1683 WP_109375950.1 RluA family pseudouridine synthase -
BST98_RS19175 1055718..1055978 + 261 WP_036765838.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
BST98_RS19180 1055968..1056228 + 261 WP_036765839.1 Txe/YoeB family addiction module toxin Toxin
BST98_RS19185 1056286..1056540 - 255 WP_036765840.1 hypothetical protein -
BST98_RS19190 1056552..1057436 - 885 WP_109375804.1 AraC family transcriptional regulator -
BST98_RS19195 1057596..1058744 + 1149 WP_109375805.1 iron-containing alcohol dehydrogenase -
BST98_RS19200 1058800..1059702 - 903 WP_109375806.1 LysR family transcriptional regulator -
BST98_RS19205 1059875..1060420 + 546 WP_197710632.1 AhpC/TSA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10319.86 Da        Isoelectric Point: 9.7118

>T69302 WP_036765839.1 NZ_CP018298:1055968-1056228 [Photobacterium damselae]
MMINFTPNAWDDYLYWQSQDKKTLKRINKLIENCVRTPFEGIGKPEPLKDNLSGYWSRRIDDTHRLVYKATQDTLVIVAV
RFHYQK

Download         Length: 261 bp

>T69302 NZ_CP018298:1055968-1056228 [Photobacterium damselae]
ATGATGATTAATTTCACGCCTAACGCTTGGGATGATTACTTATACTGGCAATCTCAAGATAAGAAGACTTTAAAACGAAT
CAATAAACTGATTGAGAATTGTGTTAGAACGCCGTTCGAAGGAATTGGAAAGCCTGAACCATTGAAAGATAACTTATCAG
GCTATTGGTCGCGACGCATTGATGATACACATAGATTAGTCTATAAAGCTACTCAAGATACTTTAGTCATTGTTGCTGTT
CGGTTTCACTACCAAAAGTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9718.89 Da        Isoelectric Point: 4.3167

>AT69302 WP_036765838.1 NZ_CP018298:1055718-1055978 [Photobacterium damselae]
MTVLSFSEVRGNFKKVCDQVVDDCDAVVIHRRDADNVVLMSESEFNSWKETMYLMSNPVNAANLLESIKQAECGNVQTHE
LLSHDD

Download         Length: 261 bp

>AT69302 NZ_CP018298:1055718-1055978 [Photobacterium damselae]
ATGACCGTTTTGAGTTTTTCTGAAGTTCGAGGCAATTTTAAAAAAGTATGCGATCAAGTCGTTGATGATTGCGATGCAGT
AGTTATCCATCGACGTGATGCAGATAATGTCGTGCTTATGTCTGAATCTGAGTTTAATAGCTGGAAGGAAACGATGTATC
TCATGTCTAATCCTGTGAATGCTGCAAACTTACTTGAATCAATAAAACAAGCTGAATGTGGTAATGTACAGACACATGAG
CTACTAAGCCATGATGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2T3QIJ8

Antitoxin

Source ID Structure
AlphaFold DB A0A2T3QIT0

References