Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | symE-agrB/SymE(toxin) |
Location | 5413730..5414142 | Replicon | chromosome |
Accession | NZ_CP018241 | ||
Organism | Escherichia coli strain 319 |
Toxin (Protein)
Gene name | symE | Uniprot ID | Q8FA88 |
Locus tag | BFL24_RS29455 | Protein ID | WP_000132630.1 |
Coordinates | 5413730..5414071 (-) | Length | 114 a.a. |
Antitoxin (RNA)
Gene name | agrB | ||
Locus tag | - | ||
Coordinates | 5414066..5414142 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BFL24_RS32080 | 5409298..5409498 | + | 201 | WP_001310455.1 | hypothetical protein | - |
BFL24_RS29430 | 5409741..5411153 | - | 1413 | WP_000199295.1 | PLP-dependent aminotransferase family protein | - |
BFL24_RS29440 | 5411330..5411494 | + | 165 | WP_000394274.1 | DUF1127 domain-containing protein | - |
BFL24_RS29445 | 5411591..5412472 | + | 882 | WP_001304007.1 | DUF262 domain-containing protein | - |
BFL24_RS29450 | 5412520..5413683 | + | 1164 | WP_001304006.1 | DUF1524 domain-containing protein | - |
BFL24_RS29455 | 5413730..5414071 | - | 342 | WP_000132630.1 | endoribonuclease SymE | Toxin |
- | 5414066..5414142 | + | 77 | NuclAT_13 | - | Antitoxin |
- | 5414066..5414142 | + | 77 | NuclAT_13 | - | Antitoxin |
- | 5414066..5414142 | + | 77 | NuclAT_13 | - | Antitoxin |
- | 5414066..5414142 | + | 77 | NuclAT_13 | - | Antitoxin |
- | 5414066..5414142 | + | 77 | NuclAT_14 | - | Antitoxin |
- | 5414066..5414142 | + | 77 | NuclAT_14 | - | Antitoxin |
- | 5414066..5414142 | + | 77 | NuclAT_14 | - | Antitoxin |
- | 5414066..5414142 | + | 77 | NuclAT_14 | - | Antitoxin |
BFL24_RS29460 | 5414292..5416046 | - | 1755 | WP_000110094.1 | restriction endonuclease subunit S | - |
BFL24_RS29465 | 5416046..5417515 | - | 1470 | WP_001302468.1 | type I restriction-modification system subunit M | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Genomic island | - | - | 5403223..5421943 | 18720 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 114 a.a. Molecular weight: 12294.13 Da Isoelectric Point: 8.4982
>T69090 WP_000132630.1 NZ_CP018241:c5414071-5413730 [Escherichia coli]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTVVDVKVMEGCIVLTAQPPAAAESE
LMQSLRQVCKLSARKQRQVQEFIGVIAGKQKVA
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTVVDVKVMEGCIVLTAQPPAAAESE
LMQSLRQVCKLSARKQRQVQEFIGVIAGKQKVA
Download Length: 342 bp
>T69090 NZ_CP018241:c5414071-5413730 [Escherichia coli]
ATGACTGATACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGTCGTTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CCGGCACGGTGGTAGATGTCAAAGTGATGGAAGGCTGTATTGTCCTCACCGCCCAACCACCCGCCGCCGCCGAGAGCGAA
CTGATGCAGTCGCTGCGCCAGGTGTGCAAGCTGTCGGCGCGTAAACAAAGGCAGGTGCAGGAGTTTATTGGGGTGATTGC
GGGTAAACAGAAAGTTGCCTGA
ATGACTGATACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGTCGTTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CCGGCACGGTGGTAGATGTCAAAGTGATGGAAGGCTGTATTGTCCTCACCGCCCAACCACCCGCCGCCGCCGAGAGCGAA
CTGATGCAGTCGCTGCGCCAGGTGTGCAAGCTGTCGGCGCGTAAACAAAGGCAGGTGCAGGAGTTTATTGGGGTGATTGC
GGGTAAACAGAAAGTTGCCTGA
Antitoxin
Download Length: 77 bp
>AT69090 NZ_CP018241:5414066-5414142 [Escherichia coli]
AGTCATAACTGCTATTCCCTATAAATAGTGATTGTGATTAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT
AGTCATAACTGCTATTCCCTATAAATAGTGATTGTGATTAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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