Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/COG4683-HTH_37 |
| Location | 125831..126488 | Replicon | plasmid pUO-STmRV1 |
| Accession | NZ_CP018220 | ||
| Organism | Salmonella enterica subsp. enterica strain LSP 389/97 | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | U3PDC3 |
| Locus tag | A5895_RS26240 | Protein ID | WP_000270043.1 |
| Coordinates | 126138..126488 (-) | Length | 117 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | A5895_RS26235 | Protein ID | WP_000124640.1 |
| Coordinates | 125831..126133 (-) | Length | 101 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| A5895_RS26185 | 120936..121298 | + | 363 | WP_021293829.1 | hypothetical protein | - |
| A5895_RS26190 | 121291..122289 | + | 999 | WP_025989273.1 | hypothetical protein | - |
| A5895_RS26195 | 122299..122745 | + | 447 | WP_000919345.1 | Fe3+-siderophore ABC transporter permease | - |
| A5895_RS26200 | 122742..123260 | + | 519 | WP_011872844.1 | hypothetical protein | - |
| A5895_RS26205 | 123260..123490 | + | 231 | WP_000972664.1 | hypothetical protein | - |
| A5895_RS26210 | 123477..124334 | + | 858 | WP_001167033.1 | hypothetical protein | - |
| A5895_RS26220 | 124565..125092 | + | 528 | WP_011872875.1 | thermonuclease family protein | - |
| A5895_RS26225 | 125150..125422 | + | 273 | WP_020833605.1 | HU family DNA-binding protein | - |
| A5895_RS26230 | 125511..125804 | + | 294 | WP_025989274.1 | chromosome segregation protein ParM | - |
| A5895_RS26235 | 125831..126133 | - | 303 | WP_000124640.1 | XRE family transcriptional regulator | Antitoxin |
| A5895_RS26240 | 126138..126488 | - | 351 | WP_000270043.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| A5895_RS26245 | 126651..127199 | + | 549 | WP_058650151.1 | hypothetical protein | - |
| A5895_RS26255 | 127540..127734 | + | 195 | WP_000343597.1 | hypothetical protein | - |
| A5895_RS26260 | 127745..128116 | + | 372 | WP_000516916.1 | hypothetical protein | - |
| A5895_RS26265 | 128109..128579 | + | 471 | WP_001281821.1 | hypothetical protein | - |
| A5895_RS26270 | 128594..128929 | - | 336 | WP_000683477.1 | hypothetical protein | - |
| A5895_RS26275 | 129026..129514 | + | 489 | WP_001273096.1 | DUF1643 domain-containing protein | - |
| A5895_RS26280 | 129517..130014 | + | 498 | WP_000062185.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..197365 | 197365 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 17237.68 Da Isoelectric Point: 5.5500
>T68949 WP_000270043.1 NZ_CP018220:c126488-126138 [Salmonella enterica subsp. enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
Download Length: 351 bp
>T68949 NZ_CP018220:c126488-126138 [Salmonella enterica subsp. enterica]
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Antitoxin
Download Length: 101 a.a. Molecular weight: 14882.85 Da Isoelectric Point: 5.5500
>AT68949 WP_000124640.1 NZ_CP018220:c126133-125831 [Salmonella enterica subsp. enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
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Download Length: 303 bp
>AT68949 NZ_CP018220:c126133-125831 [Salmonella enterica subsp. enterica]
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Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|