Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2210758..2211021 Replicon chromosome
Accession NZ_CP018205
Organism Staphylococcus aureus strain HG001 isolate RN1

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag BSR30_RS11775 Protein ID WP_001802298.1
Coordinates 2210917..2211021 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2210758..2210922 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSR30_RS11755 2206998..2207663 - 666 WP_001024094.1 SDR family oxidoreductase -
BSR30_RS11760 2207815..2208135 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
BSR30_RS11765 2208137..2209117 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
BSR30_RS11770 2209383..2210474 + 1092 WP_000495671.1 lytic regulatory protein -
- 2210758..2210922 + 165 - - Antitoxin
BSR30_RS11775 2210917..2211021 - 105 WP_001802298.1 hypothetical protein Toxin
BSR30_RS15220 2211182..2211665 - 484 Protein_2168 recombinase family protein -
BSR30_RS11785 2211708..2212844 - 1137 WP_000115562.1 SAP domain-containing protein -
BSR30_RS11790 2213133..2213225 + 93 WP_001790138.1 hypothetical protein -
BSR30_RS11795 2213930..2214787 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
BSR30_RS11800 2214855..2215637 - 783 WP_000908177.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T68910 WP_001802298.1 NZ_CP018205:c2211021-2210917 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T68910 NZ_CP018205:c2211021-2210917 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT68910 NZ_CP018205:2210758-2210922 [Staphylococcus aureus]
GTAGCAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References