Detailed information of TA system TA068901

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1831603..1831785
• Replicon: chromosome
• Accession: NZ_CP018205
• Organism: Staphylococcus aureus strain HG001 isolate RN1

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: BSR30_RS15190
• Protein ID: WP_001801861.1
• Coordinates: 1831603..1831698 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1831726..1831785 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BSR30_RS09275	1827263..1827889	+	627	WP_000669046.1	hypothetical protein	-
BSR30_RS09280	1827930..1828274	+	345	WP_000627551.1	DUF3969 family protein	-
BSR30_RS09285	1828372..1828923	+	552	WP_000414205.1	hypothetical protein	-
BSR30_RS09290	1829141..1829782	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
BSR30_RS09295	1829896..1830081	-	186	WP_000809857.1	hypothetical protein	-
BSR30_RS09300	1830083..1830259	-	177	WP_000375476.1	hypothetical protein	-
BSR30_RS09305	1830270..1830653	-	384	WP_000070812.1	hypothetical protein	-
BSR30_RS09320	1831257..1831400	-	144	WP_001549059.1	transposase	-
BSR30_RS15190	1831603..1831698	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1831726..1831785	-	60	-	-	Antitoxin
BSR30_RS09325	1831821..1831922	+	102	WP_001791893.1	hypothetical protein	-
BSR30_RS09330	1831900..1832076	-	177	Protein_1746	transposase	-
BSR30_RS09335	1832270..1832647	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA	1805576..1864874	59298

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T68901 WP_001801861.1 NZ_CP018205:1831603-1831698 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T68901 NZ_CP018205:1831603-1831698 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT68901 NZ_CP018205:c1831785-1831726 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin