Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 1799648..1800298 Replicon chromosome
Accession NZ_CP018034
Organism Glaesserella parasuis str. Nagasaki

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag A2U21_RS09210 Protein ID WP_021110393.1
Coordinates 1799648..1799986 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag A2U21_RS09215 Protein ID WP_005710405.1
Coordinates 1799990..1800298 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A2U21_RS09175 1794745..1796892 + 2148 WP_021110395.1 cadmium-translocating P-type ATPase -
A2U21_RS09185 1797375..1798814 - 1440 WP_021110394.1 glutamate--tRNA ligase -
A2U21_RS09210 1799648..1799986 + 339 WP_021110393.1 selenocysteine synthase Toxin
A2U21_RS09215 1799990..1800298 + 309 WP_005710405.1 helix-turn-helix domain-containing protein Antitoxin
A2U21_RS09220 1800499..1801659 + 1161 WP_010786053.1 bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN -
A2U21_RS09225 1801759..1802340 + 582 WP_021110392.1 type IV pilus biogenesis/stability protein PilW -
A2U21_RS09230 1802401..1803336 + 936 WP_021110391.1 KpsF/GutQ family sugar-phosphate isomerase -
A2U21_RS09235 1803336..1803815 + 480 WP_021110390.1 transcription elongation factor GreB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-86)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 13302.34 Da        Isoelectric Point: 10.0084

>T68598 WP_021110393.1 NZ_CP018034:1799648-1799986 [Glaesserella parasuis str. Nagasaki]
MNVTFVELPPFEEYRKKYLDDDTFRLLQNELLKFPDKGELIQGTGGLRKLRIVDIIRQKGKRGGARVIYYYYVRGKQVWL
FHAYNKNQQDDLSNEERVVLANTLSYLKSLVR

Download         Length: 339 bp

>T68598 NZ_CP018034:1799648-1799986 [Glaesserella parasuis str. Nagasaki]
ATGAATGTCACTTTTGTGGAATTACCGCCTTTTGAGGAATATAGAAAAAAGTATCTTGACGATGACACATTTAGATTATT
ACAAAATGAGTTATTAAAATTTCCCGATAAGGGAGAGCTTATTCAAGGTACTGGGGGACTAAGAAAATTGCGTATTGTAG
ATATTATTAGACAAAAAGGAAAAAGAGGCGGAGCTAGGGTAATCTATTACTATTATGTGCGAGGGAAACAAGTTTGGTTG
TTCCACGCCTACAATAAAAACCAACAAGACGATTTATCTAATGAAGAACGTGTGGTTTTGGCGAATACATTAAGCTATTT
AAAATCTTTAGTGAGGTAA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11539.61 Da        Isoelectric Point: 10.2919

>AT68598 WP_005710405.1 NZ_CP018034:1799990-1800298 [Glaesserella parasuis str. Nagasaki]
MGKLFNELMEGMQALELHLQGKITLKTTVVEVPDPIVITPEEVKAIRQKLNLSQAVFARKLHTSVRTYQGWEQGRTKPNP
QAVLLLKMVEKSPKTFEQIASI

Download         Length: 309 bp

>AT68598 NZ_CP018034:1799990-1800298 [Glaesserella parasuis str. Nagasaki]
ATGGGAAAATTATTTAATGAACTAATGGAAGGGATGCAAGCATTAGAGTTACACTTACAAGGCAAAATTACACTAAAAAC
CACTGTCGTGGAAGTTCCTGATCCGATAGTGATTACCCCCGAAGAAGTGAAAGCTATTCGTCAGAAATTAAATCTTTCAC
AAGCCGTTTTTGCTCGTAAATTACACACTTCGGTGAGAACTTATCAAGGCTGGGAGCAAGGAAGAACAAAACCTAATCCA
CAAGCGGTTTTATTATTAAAAATGGTTGAAAAATCACCAAAAACATTTGAGCAGATTGCGAGCATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References