Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 127624..128147 Replicon plasmid unnamed5
Accession NZ_CP017945
Organism Phyllobacterium zundukense strain Tri-48

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag BLM14_RS30450 Protein ID WP_100003798.1
Coordinates 127624..127896 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag BLM14_RS30455 Protein ID WP_100003799.1
Coordinates 127893..128147 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BLM14_RS30430 122905..124710 - 1806 WP_100003794.1 metallophosphoesterase -
BLM14_RS30435 124925..125755 + 831 WP_100003795.1 MBL fold metallo-hydrolase -
BLM14_RS30440 125752..126513 - 762 WP_100003796.1 polysaccharide deacetylase family protein -
BLM14_RS30445 126510..127604 - 1095 WP_100003797.1 glycosyltransferase family 4 protein -
BLM14_RS30450 127624..127896 - 273 WP_100003798.1 Txe/YoeB family addiction module toxin Toxin
BLM14_RS30455 127893..128147 - 255 WP_100003799.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
BLM14_RS30460 128371..130076 + 1706 Protein_132 adenylate/guanylate cyclase domain-containing protein -
BLM14_RS30465 130127..130495 + 369 Protein_133 Bcr/CflA family drug resistance efflux transporter -
BLM14_RS30470 130555..131427 + 873 WP_100003800.1 FkbM family methyltransferase -
BLM14_RS30475 131407..131889 - 483 WP_100003801.1 hypothetical protein -
BLM14_RS30480 132303..132821 + 519 WP_100003802.1 sigma-70 family RNA polymerase sigma factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - flhA / fliQ / fliP / flgI / motA 1..211008 211008


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10928.40 Da        Isoelectric Point: 9.9066

>T68392 WP_100003798.1 NZ_CP017945:c127896-127624 [Phyllobacterium zundukense]
VRLTWTERGWQDYLYWQQMGDKILKRINELIRDTERHPFQGIGKPEPLRNEMSGWWSRRINHEHRLVYRVSGKADTQALE
ITACRFHYGT

Download         Length: 273 bp

>T68392 NZ_CP017945:c127896-127624 [Phyllobacterium zundukense]
GTGAGGCTCACGTGGACCGAACGCGGCTGGCAAGATTACCTTTATTGGCAACAGATGGGTGACAAGATTCTCAAGCGGAT
CAATGAGTTGATCCGCGACACGGAGCGGCATCCATTTCAGGGTATTGGGAAACCAGAGCCTCTTCGCAATGAGATGTCGG
GCTGGTGGTCCCGCCGCATCAACCATGAACATCGTCTGGTATATCGCGTTTCGGGAAAAGCCGATACGCAAGCATTGGAA
ATCACCGCTTGCCGGTTTCATTATGGAACCTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9631.94 Da        Isoelectric Point: 4.8129

>AT68392 WP_100003799.1 NZ_CP017945:c128147-127893 [Phyllobacterium zundukense]
MAQVTFTELRNNLATHFDRIEADRVEMVVTRQNHDPMVIIPLSEWEGMKETLYLLSTPANARHLRESIADANAGKLTERD
LIEP

Download         Length: 255 bp

>AT68392 NZ_CP017945:c128147-127893 [Phyllobacterium zundukense]
ATGGCACAAGTTACATTCACGGAGTTGCGCAACAATCTTGCAACGCATTTCGACAGGATCGAAGCAGATCGCGTTGAGAT
GGTGGTGACGCGTCAGAATCATGATCCTATGGTCATTATTCCATTGTCAGAATGGGAGGGCATGAAGGAGACGCTTTATC
TTCTCAGCACACCCGCGAACGCACGCCATTTGCGGGAATCGATTGCTGACGCCAATGCCGGCAAGCTTACGGAACGGGAT
TTGATTGAACCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References