Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2372869..2373053 Replicon chromosome
Accession NZ_CP017685
Organism Staphylococcus aureus strain CFSAN007835

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag AB525_RS12145 Protein ID WP_000482647.1
Coordinates 2372946..2373053 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2372869..2372929 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AB525_RS12125 2368455..2368622 - 168 WP_031785511.1 hypothetical protein -
AB525_RS12135 2368853..2370586 - 1734 WP_000488492.1 ABC transporter ATP-binding protein/permease -
AB525_RS12140 2370635..2372374 - 1740 WP_001064831.1 ABC transporter ATP-binding protein/permease -
AB525_RS13620 2372752..2372919 - 168 WP_000301894.1 hypothetical protein -
- 2372869..2372929 + 61 - - Antitoxin
AB525_RS12145 2372946..2373053 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
AB525_RS12150 2373187..2373573 - 387 WP_000779354.1 flippase GtxA -
AB525_RS12155 2373841..2374983 + 1143 WP_001176860.1 glycerate kinase -
AB525_RS12160 2375043..2375702 + 660 WP_000831298.1 membrane protein -
AB525_RS12165 2375882..2377093 + 1212 WP_001191975.1 multidrug effflux MFS transporter -
AB525_RS12170 2377216..2377689 - 474 WP_000456491.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T68054 WP_000482647.1 NZ_CP017685:c2373053-2372946 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T68054 NZ_CP017685:c2373053-2372946 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT68054 NZ_CP017685:2372869-2372929 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References