Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2551511..2551695 Replicon chromosome
Accession NZ_CP017684
Organism Staphylococcus aureus strain CFSAN007847

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag AB520_RS13300 Protein ID WP_000482647.1
Coordinates 2551588..2551695 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2551511..2551571 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AB520_RS13275 2547021..2547188 - 168 Protein_2464 hypothetical protein -
AB520_RS13285 2547419..2549152 - 1734 WP_000486505.1 ABC transporter ATP-binding protein/permease -
AB520_RS13290 2549177..2550940 - 1764 WP_099119681.1 ABC transporter ATP-binding protein/permease -
- 2551511..2551571 + 61 - - Antitoxin
AB520_RS13300 2551588..2551695 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
AB520_RS13305 2551829..2552215 - 387 WP_000779351.1 flippase GtxA -
AB520_RS13310 2552483..2553625 + 1143 WP_001176855.1 glycerate kinase -
AB520_RS13315 2553685..2554344 + 660 WP_000831298.1 membrane protein -
AB520_RS13320 2554526..2555737 + 1212 WP_001191919.1 multidrug effflux MFS transporter -
AB520_RS13325 2555860..2556333 - 474 WP_000456496.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T68047 WP_000482647.1 NZ_CP017684:c2551695-2551588 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T68047 NZ_CP017684:c2551695-2551588 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT68047 NZ_CP017684:2551511-2551571 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References