Detailed information of TA system TA068034

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1868839..1869019
• Replicon: chromosome
• Accession: NZ_CP017684
• Organism: Staphylococcus aureus strain CFSAN007847

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: AB520_RS14800
• Protein ID: WP_001801861.1
• Coordinates: 1868839..1868934 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1868962..1869019 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AB520_RS09195	1863983..1864609	+	627	WP_000669038.1	hypothetical protein	-
AB520_RS09200	1864650..1864994	+	345	WP_000627550.1	DUF3969 family protein	-
AB520_RS09205	1865092..1865664	+	573	WP_000414222.1	hypothetical protein	-
AB520_RS09210	1865813..1867180	-	1368	WP_001093574.1	FRG domain-containing protein	-
AB520_RS09215	1867180..1867749	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
AB520_RS09220	1867942..1868388	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
AB520_RS14800	1868839..1868934	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1868962..1869019	-	58	-	-	Antitoxin
AB520_RS09230	1869057..1869158	+	102	WP_001791232.1	hypothetical protein	-
AB520_RS09235	1869333..1869776	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
AB520_RS09245	1871493..1871882	-	390	WP_099119646.1	DUF1433 domain-containing protein	-
AB520_RS09250	1871882..1872324	-	443	Protein_1744	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hysA / selk	1862217..1952199	89982

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T68034 WP_001801861.1 NZ_CP017684:1868839-1868934 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T68034 NZ_CP017684:1868839-1868934 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT68034 NZ_CP017684:c1869019-1868962 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin