Detailed information of TA system TA068033

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 997362..997611
• Replicon: chromosome
• Accession: NZ_CP017684
• Organism: Staphylococcus aureus strain CFSAN007847

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: AB520_RS04925
• Protein ID: WP_000623369.1
• Coordinates: 997362..997469 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	997464..997611 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AB520_RS04900	994035..994604	-	570	WP_000287265.1	competence protein ComK	-
AB520_RS04905	994814..995032	+	219	WP_000876825.1	IDEAL domain-containing protein	-
AB520_RS04910	995113..996099	-	987	WP_000668820.1	lipoate--protein ligase	-
AB520_RS04915	996298..996474	+	177	WP_000214898.1	YkvS family protein	-
AB520_RS04920	996489..997091	+	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
AB520_RS04925	997362..997469	+	108	WP_000623369.1	putative holin-like toxin	Toxin
-	997464..997611	-	148	-	-	Antitoxin
AB520_RS04930	998008..998109	+	102	WP_001790623.1	hypothetical protein	-
AB520_RS04935	998119..998391	+	273	WP_001794574.1	lactococcin 972 family bacteriocin	-
AB520_RS04940	998435..1000399	+	1965	WP_000870819.1	bacteriocin-associated integral membrane family protein	-
AB520_RS04945	1000402..1000722	+	321	WP_000873929.1	YxeA family protein	-
AB520_RS04950	1000719..1001360	+	642	WP_000571191.1	ABC transporter ATP-binding protein	-
AB520_RS04955	1001448..1001738	-	291	WP_001791476.1	hypothetical protein	-
AB520_RS04960	1002079..1002366	+	288	WP_000410718.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T68033 WP_000623369.1 NZ_CP017684:997362-997469 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T68033 NZ_CP017684:997362-997469 [Staphylococcus aureus]
GTGATATCTATTGCAAACGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTCACTTTCATTGGTGTAGTAGTCGC
AATAATTAATTTAAACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 148 bp

>AT68033 NZ_CP017684:c997611-997464 [Staphylococcus aureus]
CAATTAAATAAAAGATATGTTACTATAAAAATGTAAAAAGACGACATGCAGGAACATGTCGCCTAATGAGCCCGTTAAAA
AGACGGTGACTAAATGAGATTTTCTTTAACCATCATTCGTTGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Antitoxin