Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2182872..2183088 Replicon chromosome
Accession NZ_CP017682
Organism Staphylococcus aureus strain CFSAN007850

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag AB526_RS11270 Protein ID WP_001802298.1
Coordinates 2182984..2183088 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2182872..2182927 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AB526_RS11250 2179078..2179743 - 666 WP_001024095.1 SDR family oxidoreductase -
AB526_RS11255 2179895..2180215 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
AB526_RS11260 2180217..2181194 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
AB526_RS11265 2181460..2182551 + 1092 WP_000495669.1 hypothetical protein -
- 2182872..2182927 + 56 - - Antitoxin
AB526_RS11270 2182984..2183088 - 105 WP_001802298.1 hypothetical protein Toxin
AB526_RS11280 2183768..2183926 + 159 WP_001792784.1 hypothetical protein -
AB526_RS11290 2184584..2185441 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
AB526_RS11295 2185509..2186291 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T68026 WP_001802298.1 NZ_CP017682:c2183088-2182984 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T68026 NZ_CP017682:c2183088-2182984 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT68026 NZ_CP017682:2182872-2182927 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References