Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2433391..2433575 Replicon chromosome
Accession NZ_CP017680
Organism Staphylococcus aureus strain CFSAN007851

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag AB454_RS12640 Protein ID WP_000482647.1
Coordinates 2433468..2433575 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2433391..2433451 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AB454_RS12615 2428865..2429032 - 168 WP_001790576.1 hypothetical protein -
AB454_RS12625 2429263..2430996 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
AB454_RS12630 2431021..2432784 - 1764 WP_001064816.1 ABC transporter ATP-binding protein/permease -
- 2433391..2433451 + 61 - - Antitoxin
AB454_RS12640 2433468..2433575 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
AB454_RS12645 2433709..2434095 - 387 WP_000779360.1 flippase GtxA -
AB454_RS12650 2434353..2435495 + 1143 WP_001176871.1 glycerate kinase -
AB454_RS12655 2435555..2436214 + 660 WP_000831301.1 membrane protein -
AB454_RS12660 2436396..2437607 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
AB454_RS12665 2437730..2438203 - 474 WP_000456497.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T68012 WP_000482647.1 NZ_CP017680:c2433575-2433468 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T68012 NZ_CP017680:c2433575-2433468 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT68012 NZ_CP017680:2433391-2433451 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References