Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2155005..2155202 Replicon chromosome
Accession NZ_CP017680
Organism Staphylococcus aureus strain CFSAN007851

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag AB454_RS11135 Protein ID WP_001802298.1
Coordinates 2155098..2155202 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2155005..2155043 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AB454_RS11115 2151189..2151854 - 666 WP_001024095.1 SDR family oxidoreductase -
AB454_RS11120 2152006..2152326 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
AB454_RS11125 2152328..2153308 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
AB454_RS11130 2153574..2154665 + 1092 WP_000495683.1 hypothetical protein -
- 2155005..2155043 + 39 - - Antitoxin
AB454_RS11135 2155098..2155202 - 105 WP_001802298.1 hypothetical protein Toxin
AB454_RS14355 2155719..2155889 + 171 WP_001792292.1 transposase -
AB454_RS11145 2155882..2156040 + 159 WP_001792784.1 hypothetical protein -
AB454_RS11155 2156699..2157556 - 858 WP_000370917.1 Cof-type HAD-IIB family hydrolase -
AB454_RS11160 2157624..2158406 - 783 WP_000908178.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T68010 WP_001802298.1 NZ_CP017680:c2155202-2155098 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T68010 NZ_CP017680:c2155202-2155098 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 39 bp

>AT68010 NZ_CP017680:2155005-2155043 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References