Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1823175..1823357 Replicon chromosome
Accession NZ_CP017680
Organism Staphylococcus aureus strain CFSAN007851

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag AB454_RS14305 Protein ID WP_001801861.1
Coordinates 1823175..1823270 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1823298..1823357 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AB454_RS09050 1818845..1819471 + 627 WP_000669017.1 hypothetical protein -
AB454_RS09055 1819512..1819853 + 342 WP_000627541.1 DUF3969 family protein -
AB454_RS09060 1819954..1820526 + 573 WP_000414202.1 hypothetical protein -
AB454_RS09065 1820724..1821281 - 558 Protein_1696 ImmA/IrrE family metallo-endopeptidase -
AB454_RS09075 1821655..1821831 - 177 WP_000375477.1 hypothetical protein -
AB454_RS09080 1821842..1822225 - 384 WP_000070811.1 hypothetical protein -
AB454_RS09090 1822829..1822972 - 144 WP_001549059.1 transposase -
AB454_RS14305 1823175..1823270 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1823298..1823357 - 60 - - Antitoxin
AB454_RS09100 1823393..1823494 + 102 WP_001791893.1 hypothetical protein -
AB454_RS09105 1823472..1823648 - 177 Protein_1702 transposase -
AB454_RS09110 1823842..1824219 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T68000 WP_001801861.1 NZ_CP017680:1823175-1823270 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T68000 NZ_CP017680:1823175-1823270 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT68000 NZ_CP017680:c1823357-1823298 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References