Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2430353..2430537 Replicon chromosome
Accession NZ_CP017679
Organism Staphylococcus aureus strain CFSAN007883

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag AB478_RS12465 Protein ID WP_000482647.1
Coordinates 2430430..2430537 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2430353..2430413 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AB478_RS12445 2425863..2426030 - 168 WP_031845053.1 hypothetical protein -
AB478_RS12455 2426261..2427994 - 1734 WP_000488493.1 ABC transporter ATP-binding protein/permease -
AB478_RS12460 2428019..2429782 - 1764 WP_001064822.1 ABC transporter ATP-binding protein/permease -
AB478_RS14115 2430236..2430403 - 168 WP_000301893.1 hypothetical protein -
- 2430353..2430413 + 61 - - Antitoxin
AB478_RS12465 2430430..2430537 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
AB478_RS12470 2430670..2431056 - 387 WP_000779353.1 flippase GtxA -
AB478_RS12475 2431324..2432466 + 1143 WP_001176863.1 glycerate kinase -
AB478_RS12480 2432526..2433185 + 660 WP_000831298.1 membrane protein -
AB478_RS12485 2433368..2434579 + 1212 WP_001191921.1 multidrug effflux MFS transporter -
AB478_RS12490 2434702..2435175 - 474 WP_000456483.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T67997 WP_000482647.1 NZ_CP017679:c2430537-2430430 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T67997 NZ_CP017679:c2430537-2430430 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT67997 NZ_CP017679:2430353-2430413 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References