Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2143759..2144022 Replicon chromosome
Accession NZ_CP017679
Organism Staphylococcus aureus strain CFSAN007883

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag AB478_RS10935 Protein ID WP_001802298.1
Coordinates 2143918..2144022 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2143759..2143923 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AB478_RS10915 2139996..2140661 - 666 WP_001024088.1 SDR family oxidoreductase -
AB478_RS10920 2140813..2141133 + 321 WP_000139802.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
AB478_RS10925 2141135..2142112 + 978 WP_000019732.1 CDF family zinc efflux transporter CzrB -
AB478_RS10930 2142378..2143469 + 1092 WP_000495695.1 hypothetical protein -
- 2143759..2143923 + 165 - - Antitoxin
AB478_RS10935 2143918..2144022 - 105 WP_001802298.1 hypothetical protein Toxin
AB478_RS14110 2144183..2144666 - 484 Protein_2024 recombinase family protein -
AB478_RS10945 2144709..2145845 - 1137 Protein_2025 SAP domain-containing protein -
AB478_RS10950 2146134..2146226 + 93 WP_031844941.1 hypothetical protein -
AB478_RS10955 2146921..2147778 - 858 WP_031844942.1 Cof-type HAD-IIB family hydrolase -
AB478_RS10960 2147846..2148628 - 783 WP_000908190.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T67995 WP_001802298.1 NZ_CP017679:c2144022-2143918 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T67995 NZ_CP017679:c2144022-2143918 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT67995 NZ_CP017679:2143759-2143923 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References