67987

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2414791..2414975 Replicon chromosome
Accession NZ_CP017677
Organism Staphylococcus aureus strain CFSAN007894

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag AB466_RS12475 Protein ID WP_000482652.1
Coordinates 2414868..2414975 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2414791..2414851 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AB466_RS12450 2410246..2410413 - 168 Protein_2301 hypothetical protein -
AB466_RS12460 2410644..2412377 - 1734 WP_000486487.1 ABC transporter ATP-binding protein/permease -
AB466_RS12465 2412402..2414165 - 1764 WP_001064825.1 ABC transporter ATP-binding protein/permease -
- 2414791..2414851 + 61 - - Antitoxin
AB466_RS12475 2414868..2414975 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
AB466_RS12480 2415109..2415495 - 387 WP_000779360.1 flippase GtxA -
AB466_RS12485 2415763..2416905 + 1143 WP_001176863.1 glycerate kinase -
AB466_RS12490 2416965..2417624 + 660 WP_000831298.1 membrane protein -
AB466_RS12495 2417806..2419017 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
AB466_RS12500 2419140..2419613 - 474 WP_000456486.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T67987 WP_000482652.1 NZ_CP017677:c2414975-2414868 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T67987 NZ_CP017677:c2414975-2414868 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT67987 NZ_CP017677:2414791-2414851 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References