Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 4371826..4372328 Replicon chromosome
Accession NZ_CP017482
Organism Pectobacterium polaris strain NIBIO1392

Toxin (Protein)


Gene name yoeB Uniprot ID A0A6P1S0U5
Locus tag BJK05_RS19750 Protein ID WP_039482019.1
Coordinates 4371826..4372080 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A7W2E625
Locus tag BJK05_RS19755 Protein ID WP_039324900.1
Coordinates 4372077..4372328 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJK05_RS19730 4366981..4368243 - 1263 WP_095701450.1 L-rhamnose isomerase -
BJK05_RS19735 4368240..4369730 - 1491 WP_095701451.1 rhamnulokinase -
BJK05_RS19740 4370067..4370906 + 840 WP_039493893.1 HTH-type transcriptional activator RhaS -
BJK05_RS19745 4370931..4371785 + 855 WP_095701452.1 helix-turn-helix domain-containing protein -
BJK05_RS19750 4371826..4372080 - 255 WP_039482019.1 Txe/YoeB family addiction module toxin Toxin
BJK05_RS19755 4372077..4372328 - 252 WP_039324900.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
BJK05_RS19760 4372404..4374113 - 1710 WP_095701453.1 ABC transporter ATP-binding protein -
BJK05_RS19765 4374110..4374976 - 867 WP_095701454.1 ABC transporter permease -
BJK05_RS19770 4374969..4375928 - 960 WP_095701455.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10211.76 Da        Isoelectric Point: 8.0353

>T66905 WP_039482019.1 NZ_CP017482:c4372080-4371826 [Pectobacterium polaris]
VKLIWSEEAWEDYLYWQDIDKRIVKKINELIKETRRTPFEGKGKPEPLKHNLAGFWSRRITEEHRLVYAITDDAMMIAAC
RYHY

Download         Length: 255 bp

>T66905 NZ_CP017482:c4372080-4371826 [Pectobacterium polaris]
GTGAAGCTAATCTGGTCAGAAGAAGCATGGGAAGACTACCTGTACTGGCAGGACATCGATAAGCGGATAGTCAAAAAAAT
CAATGAATTAATAAAAGAAACGCGCAGAACACCTTTTGAGGGAAAAGGAAAACCAGAGCCACTTAAACATAACCTGGCTG
GTTTCTGGTCGCGCCGTATCACCGAAGAACATCGTTTAGTTTATGCCATCACCGATGACGCCATGATGATCGCCGCCTGC
CGCTACCACTATTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9367.64 Da        Isoelectric Point: 4.6119

>AT66905 WP_039324900.1 NZ_CP017482:c4372328-4372077 [Pectobacterium polaris]
MRTISYSEARQNLSATMMKTVEDRAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANAKRLMNSIESLKAGNGEERD
IIE

Download         Length: 252 bp

>AT66905 NZ_CP017482:c4372328-4372077 [Pectobacterium polaris]
ATGCGTACAATTAGCTACAGCGAAGCCCGACAAAATCTATCGGCGACCATGATGAAAACGGTCGAAGATCGTGCTCCCAT
TCTTATCACCCGACAGAATGGTGAAGCCTGCGTGCTGATGTCCCTGGAAGAGTATAACTCTCTAGAAGAAACCGCGTATT
TACTGCGTTCACCAGCCAATGCAAAAAGACTGATGAATTCAATCGAGAGCCTTAAGGCTGGCAATGGCGAAGAAAGAGAT
ATCATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6P1S0U5

Antitoxin

Source ID Structure
AlphaFold DB A0A7W2E625

References