Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 3853054..3854405 Replicon chromosome
Accession NZ_CP017482
Organism Pectobacterium polaris strain NIBIO1392

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag BJK05_RS17440 Protein ID WP_095701128.1
Coordinates 3853054..3854094 (-) Length 347 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag BJK05_RS17445 Protein ID WP_095701129.1
Coordinates 3854091..3854405 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJK05_RS17415 3849005..3850357 + 1353 WP_010296544.1 glutathione-disulfide reductase -
BJK05_RS17420 3850459..3850746 - 288 WP_095701126.1 type II toxin-antitoxin system RelE/ParE family toxin -
BJK05_RS17425 3850743..3850994 - 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
BJK05_RS17430 3851249..3852154 + 906 WP_095701127.1 siderophore-interacting protein -
BJK05_RS17435 3852188..3852943 - 756 WP_095701989.1 thiol:disulfide interchange protein DsbG -
BJK05_RS17440 3853054..3854094 - 1041 WP_095701128.1 HipA domain-containing protein Toxin
BJK05_RS17445 3854091..3854405 - 315 WP_095701129.1 HipA N-terminal domain-containing protein Antitoxin
BJK05_RS17450 3854390..3854605 - 216 WP_119888975.1 helix-turn-helix transcriptional regulator -
BJK05_RS17455 3854904..3856037 - 1134 WP_095701131.1 alkylhydroperoxidase domain protein -
BJK05_RS17460 3856034..3857068 - 1035 WP_095701132.1 putative FMN-dependent luciferase-like monooxygenase -
BJK05_RS17465 3857100..3858788 - 1689 WP_095701133.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(57-307)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 347 a.a.        Molecular weight: 39541.46 Da        Isoelectric Point: 6.5556

>T66899 WP_095701128.1 NZ_CP017482:c3854094-3853054 [Pectobacterium polaris]
MTRCRILLTPLTHEEEIATGYSRKGLKHLTGSTHASSTLRFTRQQFMHDLPQAQKGMSISGYQPKIQMVVEERAFTVVDH
QGLYILKPSPIEFPHLAENEHATMTLMARLGFAVPPHGLLRFKSEQADDEPEFAFVIQRFDRDEKTGHPIHQEQLDGAMG
IGEKFGKIHMDGRQYVSYERLALFLSKHVNDNIVFKIDLFRRIAYAYMLGNNDMHLRNFGLIHSRSGSLMLAPIYDFVSV
APYPTYFSSCFMALPLLIQEEGDEALAPGFETAYGEYLGMDFILFGQRIGLSENLTKKLLADFLKEAECVESTYRDSFMP
ADAIETTLRCYRHRLKLMSILDAERI

Download         Length: 1041 bp

>T66899 NZ_CP017482:c3854094-3853054 [Pectobacterium polaris]
ATGACAAGATGTCGAATTTTGCTGACACCGCTGACACACGAAGAAGAAATCGCCACAGGCTATAGCCGTAAAGGGTTAAA
GCATCTGACGGGATCAACGCATGCTTCCTCGACCTTACGTTTCACCCGCCAGCAATTTATGCACGACTTGCCACAAGCAC
AGAAAGGCATGAGCATCTCTGGCTATCAGCCCAAAATTCAGATGGTAGTAGAAGAACGGGCGTTTACCGTCGTTGATCAT
CAAGGGCTGTACATCCTCAAACCTTCTCCGATTGAATTTCCCCATTTGGCAGAAAACGAACACGCCACGATGACGCTAAT
GGCACGCCTGGGGTTTGCCGTTCCACCACACGGGTTACTCCGTTTTAAATCGGAGCAGGCTGATGACGAACCTGAGTTTG
CTTTCGTTATTCAGCGCTTCGACCGCGACGAAAAAACGGGTCACCCTATCCATCAGGAACAGTTGGACGGTGCGATGGGG
ATCGGTGAAAAATTCGGTAAAATACACATGGATGGCAGACAATACGTCAGTTATGAGCGGTTGGCTTTATTCCTTAGCAA
ACACGTTAATGACAATATCGTCTTCAAAATAGATCTGTTTCGCCGTATCGCTTACGCCTACATGCTGGGTAACAACGACA
TGCACCTGCGTAATTTTGGTTTGATACATTCGCGCTCAGGTTCGTTAATGCTGGCTCCCATTTATGATTTTGTTTCCGTC
GCCCCCTATCCCACCTATTTTTCTTCCTGTTTCATGGCATTGCCGCTGCTGATTCAAGAAGAGGGGGATGAGGCACTCGC
GCCAGGATTTGAAACTGCATACGGAGAATACCTTGGTATGGATTTCATTCTGTTCGGGCAACGTATCGGGCTGAGTGAAA
ACCTGACCAAAAAACTACTGGCAGACTTTCTCAAAGAAGCTGAATGTGTTGAATCAACCTATCGGGATTCCTTTATGCCT
GCGGATGCTATTGAGACAACGCTGCGGTGCTATCGACACCGCCTGAAGCTTATGAGCATTCTCGATGCAGAACGGATTTA
G

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11887.66 Da        Isoelectric Point: 9.2317

>AT66899 WP_095701129.1 NZ_CP017482:c3854405-3854091 [Pectobacterium polaris]
MRRQVKVYLYGVHIGQLSQDDEGYLFEYKKSYIGPPLSLSLPIQTGTFRSKTLPPYFASLAPEGWLRRQYSQLQHLDEKD
LFGILIQNGKNLIGAVQLIAEDKS

Download         Length: 315 bp

>AT66899 NZ_CP017482:c3854405-3854091 [Pectobacterium polaris]
ATGCGCCGTCAAGTAAAGGTCTATCTTTACGGTGTCCACATCGGCCAGTTAAGTCAGGACGATGAAGGTTATCTGTTTGA
ATATAAAAAGTCCTACATCGGCCCGCCATTATCATTGAGCCTACCGATACAGACCGGCACATTTCGCAGCAAGACATTAC
CGCCTTATTTTGCCTCATTAGCCCCCGAAGGCTGGCTCCGGCGACAGTACAGCCAGCTTCAGCATCTGGATGAGAAGGAT
TTATTTGGCATCCTCATTCAAAACGGTAAGAACCTGATCGGTGCCGTGCAACTGATCGCGGAGGATAAGTCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References